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" Biosynthesis and cellular actions of bioactive natural products "
Shogo Mori
Watanabe, Coran M. H.
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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803860
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| Doc. No
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TL48666
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| Call number
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1771836288; 10026829
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| Main Entry
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Al-Kamal, Sohaib Kamal Mahmood
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| Title & Author
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Biosynthesis and cellular actions of bioactive natural products\ Shogo MoriWatanabe, Coran M. H.
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| College
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Texas A&M University
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| Date
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2015
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| Degree
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Ph.D.
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| field of study
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Chemistry
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2015
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| Page No
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193
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| Note
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Committee members: Barondeau, David P.; Begley, Tadhg P.; Reinhart, Gregory D.
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| Note
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Place of publication: United States, Ann Arbor; ISBN=978-1-339-52557-0
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| Abstract
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The utilization of natural products as therapeutic agents has been an invaluable resource throughout medicinal history. Through the combined application of combinatorial biosynthesis, the modification of a natural product by engineered enzymes, and the isolation of new bioactive natural products, the discovery of new therapeutic agents may be achieved. This work shows the novel enzymatic interaction in the biosynthesis of a known therapeutic agent and the isolation of a new bioactive natural product.
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| Subject
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Biochemistry
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| Descriptor
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Pure sciences;Cyanobacteria;Macrolactone;Natural product;Nonribosomal peptide synthetase;Polyketide;Polyketide synthase;Streptomyces;Thioesterase
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| Added Entry
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Watanabe, Coran M. H.
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ChemistryTexas AM University
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