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" Identification of Genetic Factors in the Etiology of Autism Spectrum Disorder in Arab Families "
Yasser Ammar AlSarraj
El-Agnaf, Omar M.; El-Shanti, Hatem
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Latin Dissertation
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| Language of Document
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English
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| Record Number
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804555
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| Doc. No
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TL49387
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| Call number
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1909332738; 10285241
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| Main Entry
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Elbelazi, Samah A.
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| Title & Author
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Identification of Genetic Factors in the Etiology of Autism Spectrum Disorder in Arab Families\ Yasser Ammar AlSarrajEl-Agnaf, Omar M.; El-Shanti, Hatem
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| College
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Hamad Bin Khalifa University (Qatar)
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| Date
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2017
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| Degree
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M.S.
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| field of study
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Science and Engineering
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| student score
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2017
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| Page No
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61
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| Note
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Committee members: Abdelalim, Essam M.; Akaaboune, Mohammed; Al Thani, Dena A.
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| Note
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Place of publication: United States, Ann Arbor; ISBN=978-1-369-80566-6
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| Abstract
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Autism spectrum disorder (ASD) is a social interaction and communication impairment, associated with repetitive behaviors and interests. ASD has a high worldwide prevalence of about 1-1.5%. ASD is usually accompanied with heterogeneous phenotypic comorbidities, such as epilepsy and intellectual disability (ID). Twin studies suggest a high genetic contribution to ASD etiology, and several well-known rare genetic disorders are associated with ASD with high susceptibility contribution risk at about 0.5–1% of ASD cases. Moreover, several environmental factors and chromosomal abnormalities may increase the risk; the estimated known ASD-related genetic etiology is identifiable in about 25% of all ASD cases. Nevertheless, in about 75% of ASD cases the genetic etiologies remain elusive. The occurrence of ASD in the Middle East is not clear and there is a need to fill the gap in its clinical and genetic characterization in the Arab populations.
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| Subject
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Genetics; Bioinformatics
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| Descriptor
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Biological sciences;ASD;Autism;Whole Exome Sequencing
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| Added Entry
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El-Agnaf, Omar M.; El-Shanti, Hatem
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| Added Entry
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Science and EngineeringHamad Bin Khalifa University (Qatar)
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