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" Mass spectrometry : "
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BL
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840251
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Mass spectrometry : : an applied approach.
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| Edition Statement
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Second edition // edited by Marek Smoluch, Giuseppe Grasso, Piotr Suder, and Jerzy Silberring.
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| Publication Statement
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Hoboken, NJ :: Wiley,, 2019.
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| Series Statement
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Wiley Series on Mass Spectrometry ;
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1 online resource (xxi, 418 pages)
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| ISBN
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1119377307
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: 1119377331
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: 111937734X
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: 1119377366
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: 9781119377306
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: 9781119377337
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: 9781119377344
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: 9781119377368
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9781119377306
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Intro; Title Page; Copyright Page; Contents; List of Contributors; Preface; Chapter 1 Introduction; Chapter 2 A Brief History of Mass Spectrometry; Chapter 3 Basic Definitions; Chapter 4 Instrumentation; 4.1 Ionization Methods; 4.1.1 Electron Ioniza tion (EI); 4.1.2 Chemical Ionizatio n (CI); 4.1.2.1 Principle of Operation: Positive and Negative Ion Modes; 4.1.3 Atmospheric Pressure Ionization (API); 4.1.3.1 Atmospheric Pressure Chemical Ionization (APCI); 4.1.3.2 Electrospray Ionization (ESI); 4.1.3.3 Nanoelectrospray; 4.1.3.4 Desorption Electrospray Ionization (DESI)
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4.1.3.5 Laser Ablation Electrospray Ionization (LAESI)4.1.3.6 Photoionization; 4.1.4 Ambient Plasma-Based Ionization Techniques; 4.1.4.1 Introduction; 4.1.4.2 Direct Analysis in Real Time (DART); 4.1.4.3 Flowing Atmospheric Pressure Afterglow (FAPA); 4.1.4.4 Dielectric Barrier Discharge Ionization (DBDI); 4.1.5 Matrix-Assisted Laser Desorption/Ionization (MALDI); 4.1.5.1 Introduction; 4.1.5.2 The Role of Matrix; 4.1.5.3 Atmospheric Pressure MALDI; 4.1.5.4 MALDI Mass Spectra Interpretation; 4.1.5.5 Desorption/Ionization on Porous Silicon (DIOS)
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4.1.5.6 Surface-Enhanced Laser Desorption/Ionization (SELDI)4.1.5.7 Nanostructure-Enhanced Laser Desorption/Ionization (NALDI); 4.1.5.8 Summary; 4.1.6 Inductively Coupled Plasma Ionization (ICP); 4.1.6.1 Introduction; 4.1.6.2 ICP as a Technique of Elemental Analysis and ICP Principle; 4.1.6.3 Ionization of Elements and Ionization Efficiency; 4.1.6.4 Mechanism of ICP Formation; 4.1.6.5 Ways of Plasma View and Plasma Generation; 4.1.6.6 Sample Introduction; 4.1.6.7 Measurement in the ICP-MS Technique; 4.1.6.8 Analyzers in ICP-MS Spectrometers
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4.1.7 Secondary Ion Mass Spectrometry with Time-of-FlightAnalyzer (TOF-SIMS)4.1.7.1 Introduction; 4.1.7.2 TOF-SIMS Principle of Operation; 4.1.7.3 The Sputtering of the Sample Surface; 4.1.7.4 Ionization (Generating Secondary Ions); 4.1.7.5 Construction of TOF-SIMS; 4.1.7.6 Analytical Capabilities of TOF-SIMS; 4.1.7.7 Examples and Spectra Interpretation; 4.2 Analyzers; 4.2.1 Time of Flight (TOF); 4.2.1.1 Introduction; 4.2.1.2 The Working Rule of TOF Analyzer; 4.2.1.3 Linear Mode of Operation of TOF; 4.2.1.4 The Spread of the Kinetic Energy Regarding the Ions of the Same Mass
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4.2.1.5 Delayed Ion Extraction4.2.1.6 The Reflection Mode; 4.2.1.7 Orthogonal Acceleration TOF Analyzer; 4.2.1.8 Summary; 4.2.2 Ion Mobility Analyzer (IM); 4.2.2.1 Principle of IM Operation; 4.2.2.2 Drift Time IMS; 4.2.2.3 High Field Asymmetric Waveform Ion Mobility Spectrometer (FAIMS); 4.2.2.4 Traveling Wave Ion Guides (TWIG); 4.2.2.5 IM Spectrum; 4.2.2.6 Applications; 4.2.3 Quadrupole Mass Analyzer; 4.2.3.1 Construction and Principles of Operation of a Quadrupole; 4.2.3.2 Behavior of an Ion Inside the Quadrupole; 4.2.3.3 How Mass Spectrum Is Generated? Changes of U and V
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| Abstract
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Provides a comprehensive description of mass spectrometry basics, applications, and perspectivesMass spectrometry is a modern analytical technique, allowing for fast and ultrasensitive detection and identification of chemical species. It can serve for analysis of narcotics, counterfeit medicines, components of explosives, but also in clinical chemistry, forensic research and anti-doping analysis, for identification of clinically relevant molecules as biomarkers of various diseases. This book describes everything readers need to know about mass spectrometry--from the instrumentation to the theory and applications. It looks at all aspects of mass spectrometry, including inorganic, organic, forensic, and biological MS (paying special attention to various methodologies and data interpretation). It also contains a list of key terms for easier and faster understanding of the material by newcomers to the subject and test questions to assist lecturers. Knowing how crucial it is for young researchers to fully understand both the power of mass spectrometry and the importance of other complementary methodologies, Mass Spectrometry: An Applied Approach teaches that it should be used in conjunction with other techniques such as NMR, pharmacological tests, structural identification, molecular biology, in order to reveal the true function(s) of the identified molecule.
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Mass spectrometry.
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Spectrum analysis.
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Mass spectrometry.
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SCIENCE-- Life Sciences-- Biochemistry.
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Spectrum analysis.
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| Dewey Classification
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572/.36
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| LC Classification
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QP519.9.M3M314945 2019
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| Added Entry
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Grasso, Giuseppe,1974-
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Silberring, Jerzy,1949-
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Smoluch, Marek,1977-
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Suder, Piotr,1949-
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