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" Transformation of Human Epithelial Cells (1992) : "
editors, Bruce C Casto, Charles F Shuler.
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BL
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| Record Number
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841388
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| Main Entry
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Milo, George E
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| Title & Author
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Transformation of Human Epithelial Cells (1992) : : Molecular and Oncogenetic Mechanisms /\ editors, Bruce C Casto, Charles F Shuler.
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| Edition Statement
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First edition.
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| Publication Statement
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Boca Raton, FL :: CRC Press,, 2017.
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| Series Statement
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CRC Press Revivals
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1 online resource :: text file, PDF
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| ISBN
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1315121255
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: 135135597X
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: 1351355988
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: 9781315121253
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: 9781351355971
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: 9781351355988
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1138105031
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9781138105034
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| Contents
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Intro; Cover; Title Page; Copyright Page; PREFACE; TABLE OF CONTENTS; Chapter 1 In Vitro Cellular Aging and Immortalization; Chapter 2 Detection of Growth Factor Effects and Expression in Normal and Neoplastic Human Bronchial Epithelial Cells; Chapter 3 Human Cell Metabolism and DNA Adduction of Polycyclic Aromatic Hydrocarbons; Chapter 4 Human Esophageal Epithelial Cells: Immortalization and In Vitro Transformation; Chapter 5 Transformation of Human Endometrial Stromal Cells In Vitro
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Chapter 12 Progression from Pigment Cell Patterns to Melanom as in Platyfish-Swordtail Hybrids â#x80;#x94; Multiple Genetic Changes and a Theme for TumorigenesisIndex
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Chapter 6 Factors Influencing Growth and Differentiation of Normal and Transformed Human Mammary Epithelial Cells in CultureChapter 7 Transformation of Colon Epithelial Cells; Chapter 8 Multistep Carcinogenesis and Human Epithelial Cells; Chapter 9 Morphologic and Molecular Characterizations of Plastic Tumor Cell Phenotypes; Chapter 10 Oncogene and Tumor Suppressor Gene Involvement in Human Lung Carcinogenesis; Chapter 11 Events of Tumor Progression Associated with Carcinogen Treatment of Epithelial and Fibroblast Compared with Mutagenic Events
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| Abstract
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"This book offers a conceptual explanation of the interrelationships that exist between the stages in the progression of initiated epithelial cells in culture compared with the diverse tissue of organs and the progression of tumors from different organ sites. The fate of the modification of adducts is discussed at the molecular level. The role that modifications in hot spots in oncogenes and supressor genes play at the molecular level and how these molecular modifications can lead to an explanation of molecular control in the formation of tumor phenotypes is also examined. Researchers in cell biology and toxicology, applied pharmacology, carcinogenesis, teratogenesis, mutagenesis, and molecular toxicology will find the book useful, interesting reading."--Provided by publisher.
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Carcinogenesis.
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Cell transformation.
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Epithelium-- Cancer.
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Oncogenes.
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Carcinogenesis.
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Cell transformation.
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Epithelium-- Cancer.
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Oncogenes.
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| Dewey Classification
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616.99/4
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| LC Classification
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RC280.E66 T73 1992
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| Added Entry
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Casto, Bruce C
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Shuler, Charles F
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