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" Phosphorus dendrimers in biology and nanomedicine : "
edited by Anne-Marie Caminade, Ćedric-Olivier Turrin, Jean-Pierre Majoral.
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BL
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| Record Number
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843680
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| Title & Author
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Phosphorus dendrimers in biology and nanomedicine : : synthesis, characterization, and properties /\ edited by Anne-Marie Caminade, Ćedric-Olivier Turrin, Jean-Pierre Majoral.
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| Publication Statement
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Singapore :: Pan Stafford Publishing Pte. Ltd.,, [2018]
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1 online resource :: text file, PDF
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| ISBN
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1315110857
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: 135161729X
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: 1351617303
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: 9781315110851
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: 9781351617291
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: 9781351617307
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9789814774338
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9814774332
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| Contents
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Cover; Half title; Title; Copyright; Dedication; Contents; Preface; 1. Synthesis of Phosphorus-Containing Dendrimers; 1.1 Introduction; 1.2 Synthesis and Selected Reactivity of Dendrimers Involving Phosphorhydrazone Linkages; 1.3 Synthesis Involving P=N-P=S Linkages; 1.3.1 Accelerated Synthesis from Orthogonal Systems; 1.3.2 Growing Dendrimers inside a Dendrimer; 1.3.3 Dendritic Structures owing P=N-P=S at Each Generation; 1.3.4 P=N-P=S Linkages at the Core of Dendrons; 1.4 Hybrid Phosphorus-Viologen Dendrimers and Macromolecular Asterisks; 1.5 Onion Peel Dendritic Structures
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1.6 Janus Dendrimers1.7 Miscellenous Methods; 1.8 Conclusion; 2. Methods for Characterizing (Phosphorus) Dendrimers; 2.1 Introduction; 2.2 Spectroscopy and Spectrometry Techniques; 2.2.1 Nuclear Magnetic Resonance; 2.2.2 Mass Spectrometry; 2.2.3 X-Ray Diffraction; 2.2.4 X-Ray Methods for Chemical (Surface) Analyses; 2.2.5 Infrared and Raman Spectroscopy; 2.2.6 Ultraviolet-Visible (UV-vis) and Fluorescence Spectroscopy; 2.2.7 Characterizations Related to Chirality; 2.2.8 Electron Paramagnetic Resonance; 2.2.9 Magnetometry (SQUID; 2.2.10 Electrochemistry
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2.2.11 Laser Light Scattering (LLS) and Dynamic Light Scattering (DLS) and Coupling with Size Exclusion Chromatography (SEC2.3 Microscopy Methods; 2.3.1 Transmission Electron Microscopy; 2.3.2 Atomic Force Microscopy; 2.3.3 Polarizing Optical Microscopy; 2.4 "Physical" Characterizations; 2.4.1 Intrinsic Viscosity; 2.4.2 Differential Scanning Calorimetry (DSC) and Thermogravimetric Analyses (TGA; 2.4.3 Dielectric Spectroscopy; 2.4.4 Dipole Moments; 2.5 Conclusion; 3. EPR Characterization of Phosphorus Dendrimers as Drugs for Cancer and Neurodegenerative Diseases; 3.1 Introduction
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3.2 Interactions between P-Dendrimers and Peptides Involved in Alzheimer's and Prion Diseases3.3 Interactions between P-Dendrimers and Heparin Affecting Prion Diseases; 3.4 Kinetics of the Aggregation Process of Prion and Amyloid Peptides in the Absence and Presence of P-Dendrimers; 3.5 EPR Studies of Cu(II)-Conjugated Phosphorus Dendrimers in the Absence and Presence of Normal and Cancer Cells; 3.6 Concluding Remarks; 4. Fluorescent (Phosphorus) Dendrimers and Their Use in Biology; 4.1 Introduction; 4.2 Dendrimers with Fluorophores as Terminal Groups
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4.2.1 Full Substitution on the Surface of Dendrimers by Fluorescent Groups4.2.2 Fluorescent Groups Linked to Part of the Surface of Dendrimers; 4.3 Dendrimers with Fluorophores inside the Structure; 4.3.1 Fluorescent Groups Linked to the Internal Branching Units; 4.3.2 Fluorescent Phthalocyanine as Core of Dendrimers; 4.3.3 Fluorescent Groups Linked to the Core (Off-Center; 4.4 Two-Photon Absorption Properties of Fluorophores Linked to Dendrimers; 4.4.1 TPA Fluorescent Groups Linked to the Surface of Dendrimers; 4.4.2 TPA Fluorescent Groups at the Core of Dendrimers
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| Abstract
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"Dendrimers, which are hyperbranched synthetic macromolecules, have attracted researchers increasing interest over the last three decades owing to their numerous properties, in particular, in the fields of biology and nanomedicine. This book is an up-to-date collection of the most recent achievements in the use of dendrimers in nanomedicine, exemplified by phosphorus-containing dendrimers. Starting with the synthesis and characterization of phosphorus dendrimers, the book discusses their use as biomaterials, carriers of biological entities, and anti-inflammatory drugs; in bioimaging; and against prion diseases, Alzheimers, HIV, and cancer. It compares phosphorus dendrimers with other types of dendrimers. Supplemented with numerous references and abundant illustrations, the book opens new perspectives for the researchers working on dendrimers."--Provided by publisher.
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| Subject
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Biomedical engineering.
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Dendrimers in medicine.
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Dendrimers.
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Materials science.
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Nanomedicine.
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Polymers.
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Biomedical engineering.
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Dendrimers in medicine.
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Dendrimers.
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Materials science.
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MEDICAL / Pharmacology.
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Nanomedicine.
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Polymers.
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| Dewey Classification
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[E]
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615.1/9
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SCEC02
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SCEC0370
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SCPC13
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WB033
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WB034
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WB057
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WB061
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WB075
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[E]
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| LC Classification
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R856
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R857.D36P46 2018
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| Added Entry
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Caminade, Anne-Marie
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Majoral, J.-P., (Jean-Pierre)
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Turrin, Cédric-Olivier
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