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" Thyroid hormone nuclear receptor : "
edited by Michelina Plateroti, Jacques Samarut.
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BL
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| Record Number
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851592
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| Title & Author
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Thyroid hormone nuclear receptor : : methods and protocols /\ edited by Michelina Plateroti, Jacques Samarut.
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| Publication Statement
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New York :: Humana Press :: Springer,, [2018]
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, ©2018
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| Series Statement
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Methods in molecular biology ;; v. 1801
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| Page. NO
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1 online resource (xii, 300 pages) :: illustrations (some color)
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| ISBN
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1493979019
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: 1493979027
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: 9781493979011
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: 9781493979028
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1493979019
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9781493979011
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Abstract
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This volume aims to detail the advances in the field of Thyroid hormones (THs), namely T3 and T4, and their nuclear receptor TRs from a conceptual and methodological point of view. Chapters guide readers through a general introduction, TR's engineered mice, human genetics of TRs, control of the hypothalamus-pituitary-thyroid (HPT) axis, the relevance of the local THs production and metabolism and pathological consequences of TH/TR alterations. Non-mammalian models are also presented and discussed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Thyroid Hormone Nuclear Receptor: Methods and Protocols aims to ensure successful results in the further study of this vital field.
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| Subject
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Molecular biology.
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Thyroid hormones.
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Molecular biology.
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Thyroid hormones.
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Thyroid Hormones.
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| Dewey Classification
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573.4/74
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| LC Classification
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QP572.T5
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| Added Entry
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Plateroti, Michelina
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Samarut, Jacques
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