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" Oxidative folding of proteins : "
edited by Matthias J. Feige.
Document Type
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BL
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Record Number
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855700
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Title & Author
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Oxidative folding of proteins : : basic principles, cellular regulation and engineering /\ edited by Matthias J. Feige.
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Publication Statement
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[Cambridge] :: Royal Society of Chemistry,, [2018]
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Series Statement
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Chemical biology ;; 9
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Page. NO
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1 online resource
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ISBN
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1788013255
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: 9781788013253
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1782629904
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9781782629900
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9781788014854
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Bibliographies/Indexes
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Includes bibliographical references and index.
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Contents
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Section 1: Principles and Analysis of Disulfide Bond Formation; Disulfide Bonds in Protein Folding and Stability; Techniques to Monitor Disulfide Bond Formation and the Reduction Potential of Cysteine-Cystine Couples In vitro and In vivo; Real-time Detection of Thiol Chemistry in Single Proteins; Analysis of Disulfide Bond Formation in Therapeutic Proteins; Section 2: Disulfide Bonds in Peptides and Proteins: Structure, Function and Evolution; Evolutionary Adaptations to Cysteine-rich Peptide Folding; In vitro Refolding of Proteins; Allosteric Disulfide Bonds; Section 3: Oxidative Folding in the Cell; Disulfide Bond Formation and Isomerization in Escherichia coli; Disulfide Bond Formation in Mitochondria; Structural Insights into Disulfide Bond Formation and Protein Quality Control in the Mammalian Endoplasmic Reticulum; Mechanisms of Oxidative Protein Folding and Thiol-dependent Quality Control: Tales of Cysteines and Cystines; Disulfide Bond Formation Downstream of the Endoplasmic Reticulum; Section 4: Oxidative Folding and Cellular/Organism Homeostasis; How Microbes Cope with Oxidative Stress; Disulfide Bond Formation in the Endoplasmic Reticulum; Redox Regulation of Hsp70 Chaperone Function in the Endoplasmic Reticulum; Thioredoxin and Cellular Redox Systems: Beyong Protein Disulfide Bond Reduction; Section 5: Engineering Covalent Linkages in Peptides and Proteins; Stabilization of Peptides and Proteins by Engineered Disulfide Bonds; Genetic Code Expansion Approaches to Introduce Artificial Covalent Bonds into Proteins in Vivo
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Abstract
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With contributions from experts in the field, this book provides a comprehensive overview of the oxidative folding of cysteine-rich proteins.
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Subject
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Protein folding.
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Subject
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Protein Folding.
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Subject
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Molecular biology.
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Subject
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Protein folding.
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Subject
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SCIENCE-- Life Sciences-- Biochemistry.
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Dewey Classification
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572/.633
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LC Classification
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QP551.O85 2018
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NLM classification
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QU 55.9
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Added Entry
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Feige, Matthias J.
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