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BL
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| Record Number
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860146
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| Title & Author
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Trace elements and minerals in health and longevity /\ Marco Malavolta, Eugenio Mocchegiani, editors.
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| Publication Statement
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Cham :: Springer,, 2018.
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| Series Statement
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Healthy Ageing and Longevity ;; volume 8
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| Page. NO
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1 online resource (332 pages)
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| ISBN
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3030037428
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: 9783030037420
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303003741X
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9783030037413
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| Notes
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3.9 Conclusions.
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| Contents
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Intro; Preface; Acknowledgements; Contents; 1 Iron; 1.1 Introduction; 1.2 Iron Homeostasis Regulation; 1.3 Iron and Age Related Conditions and Diseases; 1.3.1 Iron and Cancer; 1.3.2 Iron and Atherosclerosis; 1.3.3 Iron and Cardiovascular Diseases; 1.3.4 Iron and Brain Diseases; 1.3.5 Iron and Obesity Related Disorders; 1.4 Iron Deficiency; 1.5 Recommended Iron Intake for Longevity in the Elderly; 1.6 Interaction of Iron with Drugs Prescribed in the Elderly; 1.6.1 Medications Which Absorption Can Be Decreased by Iron; 1.6.2 Medications that Decrease Iron Absorption.
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1.6.3 Medication that Increase Blood Iron Levels1.7 Iron and Species Lifespan Studies; 1.8 Conclusion; References; 2 Copper; 2.1 Introduction; 2.2 Intestinal and Hepatic Tissues Determine Whole-Body Copper Distribution; 2.3 Recommended Dietary Intake of Copper; 2.4 Essentiality, Deficiency, and Intake Related to Aging; 2.4.1 Copper Deficiency and Oxidative Stress Protection During Ageing; 2.4.2 Copper Deficiency and Inflammatory/Immune Response During Ageing; 2.4.3 Copper and Central Nervous System; 2.5 Copper and Species Longevity; 2.5.1 Yeasts; 2.5.2 Flies, Worms and Rotifers; 2.5.3 Mice.
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2.5.4 Cellular Senescence: In Vitro Models2.6 New Technology to Study the Role of Copper on the Ageing; 2.7 Copper Toxicity; 2.7.1 Excess/Toxicity and Age-Related Disease: Childhood and Ageing; 2.7.2 Neurodegenerative Diseases; 2.7.3 Treatments to Combat Metal Overload; 2.8 New Perspectives in Copper and Ageing; 2.9 Conclusive Remarks; References; 3 Selenium; 3.1 Introduction; 3.2 Selenium in the Environment; 3.3 Selenium in Human and Animal Nutrition; 3.3.1 Need for Selenium in Humans; 3.3.2 Source of Selenium in Human Diet; 3.3.3 Endemic Diseases Related to Selenium Deficiency.
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3.4 Metabolism of Selenium in the Organism3.4.1 Selenium Absorption, Distribution in the Tissues and Excretion; 3.4.2 Synthesis of Selenoproteins; 3.5 The Major Selenoproteins and Their Functions; 3.5.1 Glutathione Peroxidases; 3.5.2 Thioredoxin Reductases; 3.5.3 Iodothyronine Deiodinases; 3.5.4 Selenophosphate Synthethase 2; 3.5.5 Selenoprotein P; 3.5.6 Methionine-R-Sulfoxide Reductase (Selenoprotein R); 3.5.7 Effects of Dietary Selenium on Selenoprotein Levels; 3.6 Biological Functions of Selenium in Humans and Animals; 3.6.1 Selenium and the Immune Function.
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3.6.2 Selenium and Viral Infection3.6.3 Selenium and Thyroid Function; 3.6.4 Selenium and Brain Function; 3.6.5 Selenium and Fertility; 3.6.6 Selenium and Cardiovascular Disease; 3.6.7 Role of Selenium in Detoxification of Harmful Substances; 3.6.8 Effect of Selenium on Diabetes Risk; 3.6.9 Selenium and Cancer Risk; 3.7 Health Effects of Excess Selenium; 3.7.1 Selenium Toxicity and Tolerable Upper Level of Selenium Intake; 3.7.2 Mechanisms of Selenium Toxicity; 3.8 Selenium and Longevity; 3.8.1 Selenium Intake and Mortality Risk; 3.8.2 Selenium and Aging; 3.8.3 Selenium and Longevity.
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| Abstract
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This book describes the role of trace elements in health and longevity, pursuing a biogerontological approach. It offers essential information on the impact of trace elements on molecular and physiological processes of aging, and on their impact on health in connection with aging. The major topics covered in its 11 chapters, each dedicated to a specific trace element or mineral, are: a) Role of the element in species longevity, b) Recommended intake for longevity in animal species and in the elderly, c) Deficiency and age-related disease, d) Excess/toxicity and age-related disease, and e) Interactions with drugs prescribed in the elderly. Clinical, animal and other laboratory models of interest in aging are included, which enable a more in-depth analysis to be made. The respective chapters are a mixture of overviews and more in-depth reviews in which the mechanisms of aging are described from the point of view of their specific interactions with trace elements and minerals.
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| Subject
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Aging-- Nutritional aspects.
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| Subject
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Trace elements in nutrition.
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Aging-- Nutritional aspects.
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HEALTH FITNESS-- Healthy Living.
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HEALTH FITNESS-- Holism.
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HEALTH FITNESS-- Reference.
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MEDICAL-- Preventive Medicine.
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| Subject
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Trace elements in nutrition.
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| Dewey Classification
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613.2/85
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| LC Classification
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RC627.T7
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| Added Entry
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Malavolta, Marco.
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Mocchegiani, Eugenio.
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