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BL
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| Record Number
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860824
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| Title & Author
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New psychoactive substances : : pharmacology, clinical, forensic and analytical toxicology /\ editors: Hans H. Maurer and Simon D. Brandt.
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| Publication Statement
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Cham, Switzerland :: Springer Nature :: Springer,, 2019.
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| Series Statement
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Handbook of experimental pharmacology ;; v. 252
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| Page. NO
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1 online resource
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| ISBN
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303010561X
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: 9783030105617
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9783030105600
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| Bibliographies/Indexes
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Includes bibliographical references.
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| Contents
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Intro; Preface; Contents; Responding to New Psychoactive Substances in the European Union: Early Warning, Risk Assessment, and Control Measures; 1 Introduction; 2 The Origins of New Psychoactive Substances (NPS); 3 The Situation in Europe; 3.1 Production, Marketing, and Supply; 3.2 ``Spice, ́́Smoking Mixtures, and the Synthetic Cannabinoid Receptor Agonists; 3.3 New Synthetic Opioids and the Fentanils; 3.4 Recent Developments; 4 Responding to New Psychoactive Substances in the European Union; 4.1 Legal Framework; 4.2 European Monitoring Centre for Drugs and Drug Addiction (EMCDDA)
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3.2 Early Warning Systems: From Awareness Raising to Addressing Threats4 Conclusions; References; Self-Experiments with Psychoactive Substances: A Historical Perspective; 1 Introduction; 2 Self-Experimentation in Medicine; 3 Self-Experimentation with Psychoactive Substances; 4 Defining the Topic; 4.1 Definitions of Self-Experiments with Psychoactive Substances; 4.1.1 Controlled Self-Experiments; 4.1.2 Uncontrolled Self-Experiments; 4.1.3 ``Wild ́́Self-Experiments; 5 Self-Experimentation with New Psychoactive Substances (NPS); 6 Self-Experimentation with Various Other Psychoactive Substances
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4.3 Early Warning4.3.1 European Union Early Warning System; 4.3.2 Joint Report; 4.3.3 Risk Assessment; 4.3.4 Control Measures; 5 Conclusions; 5.1 What Is Next for New Psychoactive Substances?; References; Emergence, Diversity, and Control of New Psychoactive Substances: A Global Perspective; 1 NPS Emergence Trends; 2 Understanding NPS: Chemical Versus Effect-Based Classification; 2.1 Chemical Diversity of Synthetic Cannabinoids and Cathinones; 2.2 Effect-Based Classification of NPS; 3 International Response to NPS; 3.1 Changes in the Scope of Control of Substances
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6.1 Nitrous Oxide6.2 Cannabis; 6.3 Cocaine; 6.4 Hallucinogens; 6.4.1 Mescaline; 6.4.2 Lysergic Acid Diethylamide (LSD); 6.4.3 Nightshade Hallucinogens; 6.4.4 Fly Agaric (Amanita muscaria); 6.4.5 Salvia divinorum; 6.4.6 N, N-Dimethyltryptamine (DMT); 6.4.7 Synthetic Hallucinogenic Phenethylamines; 6.5 Entactogens/Empathogens; 6.6 Dissociatives (Ketamine); 7 Discussion; 7.1 Motives for Self-Experimentation; 7.2 Goals of Self-Experiments with Psychoactive Substances; 7.3 Ethical Issues in Self-Experimentation with Psychoactive Substances; 7.4 Kinds and Consequences of Self-Experiments
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7.5 Dangers of Self-Experimentation8 Conclusions; 8.1 What Can Be Learned from the History of Self-Experimentation?; References; Neuropharmacology of Synthetic Cathinones; 1 Introduction; 1.1 Synthetic Cathinones as Medications and Drugs of Abuse; 1.2 New Psychoactive Substances (NPS) and ``Bath Salts ́́Cathinones; 2 Molecular Mechanisms of Action; 2.1 Stimulant Drugs Target SLC6 Plasma Membrane Transporters; 2.2 Transporter Blockers Versus Substrates; 3 Methods to Study Transporter Function; 3.1 Transporter Assays in Synaptosomes; 3.2 Transporter Assays in Transfected Cells
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| Abstract
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This volume is designed to feature the pharmacology of new psychoactive substances, legislative aspects, information exchange including epidemiology, and clinical, forensic, and analytical toxicology in order to facilitate the understanding of this complex and rapidly developing phenomenon.
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| Subject
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Pharmacology, Experimental.
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| Subject
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Psychotropic drugs.
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MEDICAL-- Pharmacology.
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| Subject
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Pharmacology, Experimental.
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Psychotropic drugs.
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| Dewey Classification
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615.7/8
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| LC Classification
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RM315
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| Added Entry
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Brandt, Simon D.
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Maurer, Hans,1950-
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