| Document Type
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BL
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| Record Number
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864000
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| Title & Author
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Liver anesthesiology and critical care medicine /\ Gebhard Wagener, editor.
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| Edition Statement
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Second edition.
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| Publication Statement
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Cham :: Springer,, 2018.
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| Page. NO
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1 online resource
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| ISBN
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3030097145
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: 3319642979
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: 3319642987
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: 3319642995
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: 9783030097141
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: 9783319642970
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: 9783319642987
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: 9783319642994
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9783319642970
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| Contents
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Intro; Foreword to the First Edition; Preface to the First Edition; Preface to the Second Edition; Acknowledgments; Contents; Contributors; Part I: Physiology, Pathophysiology and Pharmacology of Liver Disease; 1: Physiology and Anatomy of the Liver; Introduction; Embryology; Macroscopic Anatomy of the Liver and the Visceral Circulation; Histology; Cellular Classification; Anatomic Lobules and Metabolic Zones; Immunological Function of the Liver; Innate and Adaptive Immunity; Oral and Allograft Tolerance; Hepatic Drug Metabolism; First Pass Metabolism.
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Hepatitis B VirusHepatitis C Virus; Pathophysiology; Liver Injury; Fibrosis; Hepatocellular Dysfunction and Portal Hypertension; Clinical Presentation and Complications; Synthetic Dysfunction; Portal Hypertension; Ascites; Spontaneous Bacterial Peritonitis; Hepatic Hydrothorax; Esophageal Varices; Portosystemic Encephalopathy; Hepatopulmonary Syndrome; Portopulmonary Hypertension; Hepatorenal Syndrome; Cirrhotic Cardiomyopathy; Portal Vein Thrombosis; Hepatocellular Carcinoma; Prognosis and Risk Stratification; Prognosis; Child-Turcotte-Pugh Scoring System; Model for End-Stage Liver Disease.
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Immunity and BacteremiaAcute Kidney Injury; Coagulation; Prognosis of ALF; King's College Criteria; Clichy Criteria; MELD and Liver Volumes; Contraindications to Liver Transplantation; Summary; References; 4: The Splanchnic and Systemic Circulation in Liver Disease; Introduction; Physiology; Portal Pressure and Hypertension; The Role of Vasopressin in Liver Disease; Summary; References; 5: Drug Metabolism in Liver Failure; Introduction; Pharmacokinetics (PK) and Pharmacodynamics (PD); Effect of Liver Faiure on Medication PK and PD; Absorption; Protein Binding and Distribution; Metabolism.
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Phase II and III Metabolism, Phase 0 and III TransportSubstrates, Inducers and Inhibitors of P450 System: Implications for Toxicity and Therapeutic Failure; Hepatic Glucose, Amino Acid, and Lipid Metabolism; Glucose Homeostasis; Protein Metabolism and Hepatic Encephalopathy; Lipid Metabolism and Nonalcoholic Fatty Liver Disease; Liver Coagulation and Fibrinolysis; Hepatic Endocrine Function; References; 2: Chronic Liver Failure and Hepatic Cirrhosis; Introduction; Epidemiology; Etiologies; Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis; Alcohol-Related Liver Disease.
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Treatment of CirrhosisGeneral Management Strategies; Indications for Liver Transplantation; Antifibrotic Therapies; Targets for Antifibrotic Agents; References; 3: Acute Hepatic Failure; Introduction; Classification of ALF; Etiologies of ALF; Paracetamol (Acetominophen) Overdose; Viral Hepatitis; Idiosyncratic Drug Reaction; Seronegative (Indeterminate); Malignancy; Vascular Insults and Ischemic Hepatitis; Metabolic; Autoimmune Hepatitis; Miscellaneous; Clinical Features and General Management; Cardiovascular; Respiratory; Neurological; Metabolic, Gastroenterology and Nutrition.
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| Abstract
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Providing anesthesiology for liver surgery and especially liver transplantation is highly complex and requires profound expertise in the physiology and pathophysiology of liver disease. This new edition incorporates the latest information in the field and remains the only available book on the topic. It focuses on the practical aspect of liver anesthesiology and critical care, while providing a comprehensive and in depth summary of the knowledge in this field. Most liver transplant centers now have dedicated teams providing anesthesia care during liver transplantations. In the last years there has been a substantial increase in knowledge and improvement in techniques in anesthesiology and critical care of patients undergoing liver surgery and transplant patients. Liver Anesthesiology and Critical Care Medicine, 2nd Edition includes new chapters on chronic liver failure and hepatic cirrhosis, preoperative risk assessment, evidence in liver anesthesiology, the splanchnic and systemic circulation in liver disease and a special focus on analgesia for liver resection including regional techniques. Written for anesthesiologists and critical care physicians caring for patients undergoing liver surgery and transplantation, this book proves to be an essential companion and review book as the number of liver surgeries with higher complexity continue to increase.
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| Subject
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Anesthesiology.
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| Subject
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Critical care medicine.
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| Subject
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Liver-- Transplantation.
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| Subject
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Anesthesiology.
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Critical care medicine.
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| Subject
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Liver-- Transplantation.
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| Subject
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MEDICAL-- Surgery-- General.
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| Dewey Classification
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617.5562
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| LC Classification
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RD546
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| Added Entry
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Wagener, Gebhard
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