Document Type
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BL
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Record Number
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864604
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Title & Author
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Drug resistance in leishmania parasites : : consequences, molecular mechanisms and possible treatments /\ Alicia Ponte-Sucre, Maritza Padrón-Nieves, editors.
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Edition Statement
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Second edition.
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Publication Statement
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Cham, Switzerland :: Springer,, 2018.
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Page. NO
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1 online resource
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ISBN
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3030089304
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: 3319741853
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: 3319741861
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: 331974187X
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: 9783030089306
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: 9783319741857
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: 9783319741864
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: 9783319741871
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9783319741857
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Notes
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Includes index.
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Contents
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Leishmaniasis : the biology of a parasite -- Determinant features in leishmaniasis -- Molecular evolution and phylogeny of leishmania -- The role of reservoirs : cananie leishmaniasis -- Epidemiology of leishmaniasis in the time of drug resistance (the miltefosine era) -- The role of the immune system in resistance to infection -- Challenges in the diagnosis, treatment and control of leishmaniasis in times of drug resistance -- Co-infection with HIV -- Visceral leishmaniasis -- American tegumentary leishmaniasis -- The challenges of effective leishmaniasis treatment -- Molecular features of drug resistant leishmania -- The role of proteomics in the study of drug resistance -- The role of ABC transporters in drug-resistant leishmania -- Functional analysis of leishmania membrane (non-ABC) transporters involved in drug resistance -- Tools and strategies to circumvent drug resistance in leishmania -- Bioinformatics in leishmania drug design -- P-glycoprotein-like transportyers in leishmania : a search for reversal agents -- The concept of fitness in leishmania.
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Abstract
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Providing a comprehensive review of the epidemiology and pathology of Leishmania and Leishmaniasis, this book offers a close examination of this parasitic disease and its resistance to drugs, including its molecular basis, consequences and possible treatments.
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Subject
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Drug resistance in microorganisms.
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Subject
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Leishmaniasis.
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Subject
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Medical parasitology.
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Subject
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Drug Resistance.
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Subject
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Leishmaniasis-- epidemiology.
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Subject
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Leishmaniasis-- pathology.
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Subject
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Drug resistance in microorganisms.
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Subject
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HEALTH FITNESS-- Diseases-- General.
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Subject
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Immunology.
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Subject
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Infectious contagious diseases.
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Subject
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Leishmaniasis.
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Subject
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Medical parasitology.
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Subject
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Medical parasitology.
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Subject
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MEDICAL-- Clinical Medicine.
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Subject
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MEDICAL-- Diseases.
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Subject
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MEDICAL-- Evidence-Based Medicine.
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Subject
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MEDICAL-- Internal Medicine.
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Subject
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Microbiology (non-medical)
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Subject
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Pharmaceutical technology.
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Subject
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Pharmacology.
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Dewey Classification
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616.9/364
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LC Classification
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RC153
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Added Entry
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Padrón-Nieves, Maritza
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Ponte-Sucre, Alicia
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