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BL
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| Record Number
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865307
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| Title & Author
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Extracellular matrix for tissue engineering and biomaterials /\ edited by Anna C. Berardi.
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| Publication Statement
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Cham, Switzerland :: Humana Press,, 2018.
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| Series Statement
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Stem cell biology and regenerative medicine,
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| Page. NO
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1 online resource (xi, 213 pages) :: illustrations (some color)
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| ISBN
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3319770233
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: 9783319770239
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9783319770215
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| Notes
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Includes index.
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| Contents
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Intro; Preface; Contents; Contributors; Abbreviations; Extracellular Matrix; 1 The Extracellular Matrix, Growth Factors and Morphogens in Biomaterial Design and Tissue Engineering; Abstract; Introduction; Key Molecular ECM Components; Prominent Role of the Proteoglycans and Glycosaminoglycans; Fibrous Proteins and Adhesive Glycoproteins; Growth Factors; Protease Activity and Role of Proteolytic Enzyme in ECM; Extracellular Vesicles in the ECM Structure/Organization; Importance of ECM-Integrin Interactions; Mechanical Signals Inside the ECM; Morphogenesis.
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Human and Mouse Embryonic Stem CellsBone Marrow-Derived Hematopoietic Stem Cells; Insulin-Producing Pancreatic Islets; Neurobiology; Evaluation Criteria in Developing Cell Culture System; Future Challenges; Summary; Acknowledgements; References; 4 Extracellular Matrix: Immunity and Inflammation; Abstract; The Extracellular Matrix; Matrix Metalloproteinases (MMPs); Versican; Hyaluronan; Thrombospondins; Cells; Inflammation; Metalloproteinases and Inflammation; Versican and Inflammation; Hyaluronan and Inflammation; Thrombospondins and Inflammation; Immunity; Metalloproteinases and Immunity.
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Methods for ECM Hydrogel ProductionECM Hydrogel Characterization; Biocompatibility; Biochemical Composition; Gelation Kinetics and Mechanical Properties; Gel Topology; Tissue-Specific Hydrogels; Heart; Fat; Skin; Liver; Skeletal Muscle; Central Nervous System; Cartilage; Tendon and Ligament; Intervertebral Disk; Others; Hybrid Hydrogels; Future Directions; References; 3 Biologically Relevant Laminins in Regenerative Medicine; Abstract; Introduction; Cell Niche and Extracellular Matrix; Expanding Cells in Vitro: Future of Regenerative Medicine.
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Morphogenesis of 3D Tissue Architecture in Vivo: Folds, Tubes, and BranchesGrowth Factors and Morphogens for Tissue Engineering; Growth Factor and Morphogen Delivery Through Engineered ECM; Engineering Growth Factors and Morphogens for Interaction with Exogenous Biomaterials and for Delivery Through the Native ECM; References; 2 ECM Hydrogels for Regenerative Medicine; Abstract; Historical Development of ECM-Derived Materials; Biochemical Content; Bioinductive Properties; Antimicrobial Properties; Chemoattraction; Macrophage Polarization; Types of ECM-Derived Materials; ECM Hydrogel Formation.
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Three Pillars of Cell Niche: Growth Factors, Cell-Cell Contacts, and Niche-Specific Extracellular MatrixLaminins: Sixteen Niche-Specific Extracellular Matrix Molecules with Unique Biological Function; Laminins: Molecular Aspects and Cell Signaling; Laminins: Chains and Trimers; Molecular Interactions of Laminins; Interactions with Cell Receptors and Co-Signaling; Extracellular Matrix Interactions; Mechanotransduction; Proteolytically Degraded Forms of Laminins; Possible Antagonistic Functions of Related Laminins; Biologically Relevant Laminins for In Vitro Cell and Organoid Cultures.
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| Abstract
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This volume provides a state-of-art-report on the new methodologies in tissue engineering and developments in the biomaterials field based on the extracellular matrix-relevant discovery. Extracellular Matrix for Tissue Engineering and Biomaterials opens with an overview of the latest extracellular matrix research and in Part I, focuses on its biology and its role on cell behavior and cell fate relevant for the design of biomimetic surfaces. Part II details issues regarding the strategies currently applied in the research of biologically inspired materials and material systems for the replacement, repair and regeneration of tissues and organs. Part III presents the latest development methods applying knowledge from biology towards nanotechnology, to promote the restoration of the functionality of a living tissue. The book ranges from fundamental biology associated with tissue regeneration for the development of biomimetic approaches to controlling tissue formation, cell function, differentiation and angiogenesis using factors involved in normal tissue development and function. With the breadth and depth of the coverage of this topic, this book will serve as a valuable reference for anyone working in tissue engineering or biomaterials? from scientists, chemists and biologists through physicists, bioengineers and clinicians.
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| Subject
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Extracellular matrix.
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Tissue engineering.
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Cellular biology (cytology)
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Extracellular matrix.
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Materials science.
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SCIENCE-- Life Sciences-- Anatomy Physiology.
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| Subject
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Tissue engineering.
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| Dewey Classification
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571.5
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| LC Classification
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QH603.E93E98 2018eb
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| Added Entry
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Berardi, Anna C.
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