| Document Type
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BL
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| Record Number
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865368
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| Title & Author
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Complement activation in malaria immunity and pathogenesis /\ José A. Stoute, editor.
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| Publication Statement
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Cham, Switzerland :: Springer,, [2018]
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| Page. NO
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1 online resource :: color illustrations
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| ISBN
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3030084124
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: 3319772589
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: 3319772597
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: 9783030084127
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: 9783319772585
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: 9783319772592
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3319772570
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9783319772578
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Intro; Dedication; Preface; Contents; Contributors; The Complement System; Introduction; Classical Pathway; Lectin Pathway; Alternative Pathway; Terminal Complement Activation; Extrinsic Complement Activation Pathways; Anaphylatoxins; Complement Regulators; Soluble Complement Regulators; Surface-Bound Complement Regulators; Complement Receptors; References; Mechanisms of Complement Activation in Malaria; Introduction; Malaria Biology; Measures of Complement Activation; Immune Complexes Activate the CP of Complement.
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Complement and Malaria/Cerebral MalariaComplement in Murine Models of Cerebral Malaria; Complement Gene-Targeted and Transgenic Mice in ECM; Classical Pathway; Lectin Pathway; Alternative Pathway; Anaphylatoxin Receptors and Anaphylatoxins; C3 and C5; Terminal Pathway; Complement Phagocytic Receptors and Regulatory Proteins; Integrating the Role of Complement in ECM; Complement-Mediated Therapeutic Approaches to Cerebral Malaria; References; Complement and Malaria in Pregnancy; Global Burden of Malaria Infection During Pregnancy; Pathophysiology of Malaria in Pregnancy.
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The Role of Complement Activation in Pregnancy ComplicationsComplement Activation in Pregnancy; Complement in Non-malarial Pregnancy Pathologies; The Role of Complement Activation in Malaria in Pregnancy; Emerging Evidence of Complement Activation in MiP and Fetal Neurodevelopment; Therapeutic Potential of Targeting Complement Activation in MiP; Conclusions; References; Complement Evasion Mechanisms of the Human Pathogen Plasmodium falciparum; Merozoite Invasion into Red Blood Cells; Merozoite Surface Proteins; 6-Cysteine Family of Merozoite Surface Proteins.
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| Abstract
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References; Role of Complement in Severe Malarial Anemia; The Problem of Severe Malarial Anemia; Evidence of Complement Activation During Malaria; Evidence of Opsonoization and Changes in the Expression of Complement Regulatory Proteins on Uninfected Erythrocytes of Patients with Malaria; Genetic Association Studies; Directions for Future Research; References; Role of Complement in Cerebral Malaria; The Impact of Malaria/Cerebral Malaria; Clinical Features of Cerebral Malaria; Molecular Features of CM; Complement Synthesis in the Periphery and Central Nervous System.
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| Subject
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Complement activation.
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Immunity.
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Malaria-- Immunological aspects.
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Malaria-- Pathogenesis.
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Complement activation.
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HEALTH FITNESS-- Diseases-- General.
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Immunity.
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Immunology.
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Infectious contagious diseases.
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Malaria-- Immunological aspects.
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Medical laboratory testing techniques.
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Medical parasitology.
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MEDICAL-- Clinical Medicine.
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MEDICAL-- Diseases.
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MEDICAL-- Evidence-Based Medicine.
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MEDICAL-- Internal Medicine.
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Tropical medicine.
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Biomedicine.
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Immunology.
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Infectious Diseases.
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Laboratory Medicine.
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Parasitology.
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Tropical Medicine.
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| Dewey Classification
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616.9/362
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| LC Classification
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RC157
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| Added Entry
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Stoute, José A.
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