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" The heterogeneity of cancer metabolism / "
Anne Le, editor.
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BL
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| Record Number
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865486
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| Title & Author
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The heterogeneity of cancer metabolism /\ Anne Le, editor.
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| Publication Statement
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Cham, Switzerland :: Springer,, [2018]
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, ©2018
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| Series Statement
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Advances in experimental medicine and biology,; volume 1063
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| Page. NO
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1 online resource (xv, 183 pages) :: color. illustrations
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| ISBN
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331977736X
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: 9783319777368
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3319777351
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9783319777351
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Includes bibliographical references and index.
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| Contents
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Basic metabolism of cancer cells. Glucose metabolism in cancer / Sminu Bose, Anne Le -- Glutamine metabolism in cancer / Ting Li, Anne Le -- The heterogeneity of lipid metabolism in cancer / Joshua K. Park, Nathan J. Coffey, Aaron Limoges, Anne Le -- Heterogeneity of cancer metabolism. The multifaceted metabolism of glioblastoma / Addison Quinones, Anne Le -- The intricate metabolism of pancreatic cancers / Felipe Camelo, Anne Le -- Breast cancer metabolism / Jessica Tan, Anne Le -- Non-Hodgkin lymphoma metabolism / Brian James Kirsch, Shu-Jyuan Chang, Anne Le -- The metabolism of renal cell carcinomas and liver cancer / Tu Nguyen, Anne Le -- Different tumor microenvironments lead to different metabolic phenotypes / Marjorie Justine Antonio, Anne Le -- The intratumoral heterogeneity of cancer metabolism / Karim Nabi, Anne Le -- Relationship between cancer cells and cancer-associated fibroblasts. Metabolic relationship between cancer-associated fibroblasts and cancer cells / Christos Sazeides, Anne Le -- Targeting metabolic cross talk between cancer cells and cancer-associated fibroblasts / Jin G. Jung, Anne Le.
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| Abstract
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Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
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Cancer cells-- Metabolism.
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Cancer cells-- Molecular aspects.
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Cancer-- Treatment.
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Cancer-- Treatment.
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HEALTH FITNESS-- Diseases-- General.
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Immunology.
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MEDICAL-- Clinical Medicine.
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MEDICAL-- Diseases.
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MEDICAL-- Evidence-Based Medicine.
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MEDICAL-- Internal Medicine.
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Oncology.
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Neoplasms-- metabolism.
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Neoplasms-- therapy.
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| Dewey Classification
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616.99407
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| LC Classification
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RC269.7
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| NLM classification
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QZ 203
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| Added Entry
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Le, Anne
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