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" Evolution and selection of quantitative traits / "
Bruce Walsh, Michael Lynch.
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BL
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873969
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| Main Entry
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Walsh, Bruce,1957-
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| Title & Author
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Evolution and selection of quantitative traits /\ Bruce Walsh, Michael Lynch.
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| Edition Statement
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First edition.
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| Publication Statement
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Oxford, United Kingdom :: Oxford University Press,, 2018.
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1 online resource
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| ISBN
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0191868981
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: 0192566644
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: 9780191868986
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: 9780192566645
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0198830874
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9780198830870
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| Notes
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Sequel to: Genetics and analysis of quantitative traits / Michael Lynch, Bruce Walsh. c 1998.
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| Bibliographies/Indexes
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Includes bibliographical references and index.
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| Contents
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Cover; Evolution and Selection of Quantitative Traits; Copyright; Dedication; Contents; Preface; I: Introduction; 1: Changes in Quantitative Traits Over Time; A Brief History of the Study of the Evolution of Quantitative Traits; The Fusion of Population and Quantitative Genetics; The Ongoing Fusion of Molecular and Quantitative Genetics; The Common Thread Between Breeding and Evolution in Natural Populations; Detecting Selection in Natural Populations; The Theoretical Foundations of Evolutionary Biology; The Completeness of Evolutionary Theory
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Allele-Frequency Divergence Among PopulationsBuri's Experiment; Higher-Order Allele-Frequency Moments; Linkage Disequilibrium; Mutation-Drift Equilibrium; The Detailed Structure of Neutral Variation; The Infinite-Alleles Model and The Associated Allele-Frequency Spectrum; The Infinite-Sites Model and the Associated Site-frequency Spectrum; The Genealogical Structure of A Population; Mutation-Migration-Drift Equilibrium; Quantifying Population Structure: F ST; Mutation-migration-drift Equilibrium Values of F ST; 3: The Genetic Effective Size of a Population; General Considerations; Monoecy
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DioecyAge Structure; Variable Population Size; Partial Inbreeding; Special Systems of Mating; Population Subdivision; Selection, Recombination, and Hitchhiking Effects; Effects From Selection at Unlinked Loci; Selective Sweeps and Genetic Draft; Background Selection; 4: The Nonadaptive Forces of Evolution; Relative Power of Mutation and Genetic Drift; Nucleotide Diversity; Number of Segregating Sites; Alternative Approaches; Empirical Observations; Relative Power of Recombination and Genetic Drift; Number of Recombinational Events in a Sample of Alleles
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Nonadaptive Hypotheses and our Understanding of EvolutionOverview and Pathways Through This Volume; Evolution at One and Two Loci; Drift and Quantitative Traits; Short-term Response on a Single Character; Selection in Structured Populations; Population-genetic Models of Trait Response; Measuring Selection on Traits; Appendices; Volume 3; Notation; II: Evolution at One and Two Loci; 2: Neutral Evolution in One- and Two-Locus Systems; The Wright-Fisher Model; Loss of Heterozygosity by Random Genetic Drift; Probabilities and Times to Fixation or Loss; The Age of A Neutral Allele
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Other Approaches for Narrow Genomic IntervalsLarge-scale Analysis; Empirical Observations; Effective Population Size; Temporal Change in Allele Frequencies; Single-sample Estimators; Empirical Observations; Mutation Rate; Divergence Analysis; Short-term Enrichment; Evolution of the Mutation Rate; Recombination Rate; Evolution of the Recombination Rate; General Implications; 5: The Population Genetics of Selection; Single-Locus Selection: Two Alleles; Viability Selection; Expected Time for Allele-frequency Change; Differential Viability Selection on the Sexes; Frequency-dependent Selection
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| Abstract
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"Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important. Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 (1998) dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection (ranging from the use of genomic and historical data through to ecological field data) and examining its consequences."--
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Quantitative genetics.
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Quantitative genetics.
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SCIENCE-- Life Sciences-- Evolution.
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Quantitative Trait, Heritable.
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Evolution, Molecular.
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Genetic Variation.
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Selection, Genetic.
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| Dewey Classification
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576.5/3
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| LC Classification
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QH452.7
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| NLM classification
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QU 500
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| Added Entry
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Lynch, Michael,1951-
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Lynch, Michael,1951-
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