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" Functional hydrogels as biomaterials / "
Jun Li, Yoshihito Osda, Justin Cooper-White, editors.
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BL
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882851
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| Title & Author
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Functional hydrogels as biomaterials /\ Jun Li, Yoshihito Osda, Justin Cooper-White, editors.
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| Publication Statement
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Berlin :: Springer,, 2018.
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| Series Statement
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Springer series in biomaterials science and engineering ;; 12
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1 online resource
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| ISBN
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3662575116
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: 9783662575116
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3662575094
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9783662575093
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| Contents
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Intro; Preface; Contents; Contributors; Chapter 1: Biosynthetic Hydrogels for Cell Encapsulation; 1.1 Introduction; 1.2 Hydrogel Characteristics; 1.2.1 Hydrogel Manufacturability (Physical vs. Covalent Hydrogels); 1.2.2 Physical andMechanical Properties; 1.2.3 Degradability; 1.2.4 Biological Performance; 1.2.5 Hydrogel Materials; 1.2.5.1 Natural Hydrogels forCell Encapsulation; 1.2.5.2 Synthetic Hydrogels forCell Encapsulation; 1.3 Biosynthetic Hydrogels; 1.3.1 Polysaccharides; 1.3.2 Proteins andPeptides; 1.3.3 Growth Factors.
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1.3.4 Issues Associated withIncorporation ofNatural Molecules1.3.5 Biosynthetic Hydrogels InVitro andInVivo Performances; 1.4 Current Focus Areas forCell Encapsulation andFuture Outlooks; References; Chapter 2: Synthetic Hydrogels forExpansion ofFunctional Endothelial Cells; 2.1 Introduction; 2.2 Cell Cultivation onProtein-Free Synthetic Hydrogels; 2.3 Effect ofChemical Structure onCell Behaviors; 2.3.1 Cell Adhesion, Spreading, andMorphology; 2.3.2 Cell Proliferation; 2.4 Effect ofZeta Potential onCell Behaviors; 2.4.1 Effect ofZeta Potential onStatic Cell Behaviors.
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2.4.1.1 Effect ofZeta Potential onCell Morphology andProliferation2.4.1.2 Effect ofZeta Potential onCytoskeleton Structure andFocal Adhesion ofCells; 2.4.2 Effect ofZeta Potential onDynamic Cell Behaviors; 2.5 Relationship ofCell Behaviors andProtein Adsorption; 2.6 Application ofProtein-Free Hydrogels inBiomedical Field; 2.6.1 Platelet Compatibility oftheCell Monolayers Cultured onHydrogel Templates; 2.6.2 Surface Friction ofEC Monolayers Cultured onHydrogel Templates; 2.6.3 Selective Cell Adhesion andProliferation onMicro-ƯPatterned Hydrogel Surfaces.
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2.6.4 Tough Hydrogels forCell Adhesion andProliferation2.7 Conclusions; References; Chapter 3: Hydrogels forDirected Stem Cell Differentiation andTissue Repair; 3.1 Introduction; 3.2 Influence oftheHydrogel Properties onStem Cell Behaviour; 3.2.1 Physical Properties; 3.2.2 Chemical andBiological Functionalities; 3.2.3 2D Versus 3D Environment; 3.3 Current Hydrogel Systems Used forTissue Engineering; 3.3.1 Materials andCrosslinking Methods; 3.3.2 Smart Hydrogels; 3.4 A New Approach: Polyrotaxane Hydrogels; 3.4.1 Pseudo-polyrotaxane andPolyrotaxane Hydrogels.
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3.4.2 Polyrotaxane Hydrogels inTissue Engineering3.5 Conclusion; References; Chapter 4: Cross-Linking ofBiological Components forStem Cell Culture; 4.1 Introduction; 4.2 Chemicals forCross-Linking; 4.3 Chemically Cross-Linked Cells forCell Culture; 4.3.1 Chemically Cross-Linked Cells; 4.3.2 Pluripotent Stem Cell Culture; 4.4 Decellularized Scaffolds; 4.4.1 Maintenance ofUndifferentiated State; 4.4.2 Induction ofDifferentiation; 4.5 Conclusion andOutlook; References; Chapter 5: Hydrogels forStem Cell Encapsulation: Toward Cellular Therapy forDiabetes; 5.1 Introduction.
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| Abstract
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This book introduces readers to the latest advances in hydrogel biomaterials, mainly focusing on the emerging areas of synthetic and biopolymer hydrogels formed through specially designed chemical or physical crosslinking, and the cyclodextrin-based host-guest supramolecular self-assembly, for cell encapsulation, cell expansion, cell differentiation and tissue repair, stem cell culture, and cellular therapy and drug delivery applications. The book was written by experts at the forefront of these interdisciplinary areas and is intended for all researchers working in the fields of biomaterials and biomedical engineering, as well as medical professions. Jun Li is a Professor at the Department of Biomedical Engineering, National University of Singapore, Singapore. Yoshihito Osada is a Professor at RIKEN Advanced Science Institute, Japan. Justin Cooper-White is a Professor at the Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Australia.
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Biocompatibility.
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Biomedical materials.
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Biocompatibility.
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Biomedical materials.
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HEALTH FITNESS-- Holism.
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HEALTH FITNESS-- Reference.
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MEDICAL-- Alternative Medicine.
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MEDICAL-- Atlases.
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MEDICAL-- Essays.
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MEDICAL-- Family General Practice.
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MEDICAL-- Holistic Medicine.
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MEDICAL-- Osteopathy.
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| Dewey Classification
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610.28
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| LC Classification
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R857.M3
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| Added Entry
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Cooper-White, Justin
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Li, Jun
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Osada, Yoshihito
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