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" Glucose-sensing receptor in pancreatic beta-cells / "
edited by Itaru Kojima.
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BL
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| Record Number
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889493
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| Title & Author
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Glucose-sensing receptor in pancreatic beta-cells /\ edited by Itaru Kojima.
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| Publication Statement
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Singapore :: Springer,, [2018]
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| Page. NO
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1 online resource (v, 71 pages) :: illustrations
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| ISBN
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9789811300028
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: 981130002X
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9789811300011
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9811300011
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| Bibliographies/Indexes
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Includes bibliographical references.
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| Contents
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1 HISTORY OF THE RESEARCH ON THE GLUCOSE RECEPTOR -- 2 Cell-surface Glucoreceptor Recognizing Anomers of Glucose in Pancreatic b-cells -- 3 KATP CHANNEL-INDEPENDENT PATHWAY and THE GLUCORECEPTOR -- 4 Signaling System Activated by the Glucose-sensing Receptor -- 5 The Role of the Glucose-sensing Receptor in Glucose-induced Insulin Secretion in Pancreatic b-cells.
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| Abstract
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Since the 1970s, there has been much discussion about the "glucoreceptor" and "substrate site" and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the "glucoreceptor theory." This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells. The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: "glucoreceptor theory". Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes.
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| Subject
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Glucose-- Receptors.
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Pancreatic beta cells.
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Pancreatic beta cells.
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SCIENCE-- Life Sciences-- Biochemistry.
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| Dewey Classification
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612
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| LC Classification
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QP34-38
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QP702.G56
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| Added Entry
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Kojima, Itaru
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