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" HIV vaccines and cure : "
Linqi Zhang, Sharon R. Lewin, editors.
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BL
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| Record Number
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889629
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| Title & Author
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HIV vaccines and cure : : the path towards finding an effective cure and vaccine /\ Linqi Zhang, Sharon R. Lewin, editors.
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| Publication Statement
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Singapore :: Springer,, [2018]
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, ©2018
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| Series Statement
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Advances in experimental medicine and biology,; volume 1075
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| Page. NO
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1 online resource (xv, 318 pages) :: illustrations (chiefly color)
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| ISBN
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9789811304842
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: 981130484X
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9789811304835
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9811304831
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| Bibliographies/Indexes
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Includes bibliographical references.
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| Contents
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HIV vaccines. HIV vaccine efficacy trials: RV144 and beyond / Elizabeth Heger, Alexandra Schuetz, Sandhya Vasan -- HIV T-cell vaccines / Beatriz Mothe, Christian Brander -- HIV broadly neutralizing antibodies: VRC01 and beyond / Xueling Wu -- Structural features of broadly neutralizing antibodies and rational design of vaccine / Tongqing Zhou, Kai Xu -- Monkey models and HIV vaccine research / Zhiwei Chen -- Treatment of HIV for the prevention of transmission in discordant couples and at the population level / M. Kumi Smith, Britta L. Jewell, Timothy B. Hallett, Myron S. Cohen -- HIV cure. HIV persistence on antiretroviral therapy and barriers to a cure / Julia Marsh Sung, David M. Margolis -- The molecular biology of HIV latency / Georges Khoury, Gilles Darcis, Michelle Y. Lee, Sophie Bouchat, Benoit Van Driessche, Damian F.J. Purcell [and others] -- Cellular determinants of HIV persistence on antiretroviral therapy / Anastassia Mikhailova, Jose Carlos Valle-Casuso, Asier Sáez-Cirión -- In vitro and in vivo models of HIV latency / James B. Whitney, R. Brad Jones -- Measuring HIV persistence on antiretroviral therapy / Bethany A. Horsburgh, Sarah Palmer -- Clinical interventions in HIV cure research / Thomas Aagaard Rasmussen, Ole S. Søgaard.
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| Abstract
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"This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry"--Publisher's description.
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AIDS vaccines.
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Antiretroviral agents.
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HIV infections-- Chemotherapy.
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AIDS vaccines.
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Animal pathology diseases.
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Antiretroviral agents.
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HEALTH FITNESS-- Diseases-- General.
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HIV infections-- Chemotherapy.
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Immunology.
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Medical microbiology virology.
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MEDICAL-- Clinical Medicine.
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MEDICAL-- Diseases.
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MEDICAL-- Evidence-Based Medicine.
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MEDICAL-- Internal Medicine.
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AIDS Vaccines.
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HIV Infections-- drug therapy.
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Acquired Immunodeficiency Syndrome-- prevention control.
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Anti-Retroviral Agents.
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| Dewey Classification
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616.97/9205
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| LC Classification
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QR189.5.A33H58 2018
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| NLM classification
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WC 503.6
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| Added Entry
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Lewin, Sharon
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Zhang, Linqi
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