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BL
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| Record Number
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889806
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| Title & Author
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Functional dyspepsia : : evidences in pathophysiology and treatment /\ Kazunari Tominaga, Hiroaki Kusunoki, editors.
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| Publication Statement
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Singapore :: Springer,, 2018.
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| Page. NO
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1 online resource
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| ISBN
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9789811310744
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: 9789811310751
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: 9811310742
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: 9811310750
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9789811310737
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9811310734
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| Contents
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Intro; Preface; Contents; Part I: Etiology; Chapter 1: Definition andPrevalence; 1.1 Definition; 1.1.1 Background andHistory; 1.1.2 Uninvestigated andInvestigated Dyspepsia; 1.1.3 Subgroups; 1.1.4 Update fromRome III toRome IV; 1.2 Epidemiology; 1.3 Overlap; 1.3.1 EPS andPDS; 1.3.2 GERD andFD; 1.3.3 IBS andFD; 1.4 Pediatric FD; 1.5 Limitation ofRome IV; References; Chapter 2: Genetic Factor; 2.1 Introduction; 2.2 Familial Accumulation ofFD; 2.3 The Genotype ofGNB3 andFD; 2.4 FD Clarified by Genetic Association Study inJapan; 2.5 Conclusions; References.
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4.1.2 Gastric Distension (Mechanical Stimulation)4.2 Association oftheCNS withPathophysiology ofFD; 4.2.1 Regional Activity; 4.2.2 Serotonin (5-HT) Pathway; 4.3 Association ofAutonomic Nervous System (ANS) withPathophysiology ofFunctional Dyspepsia; 4.4 Therapeutic Possibility forFD via theNeurological Pathway; 4.4.1 Conclusions; References; Chapter 5: Neuro-gastroenterology: Enteric Nervous System; 5.1 Enteric Nervous System; 5.2 Enteric Glial Cells (EGCs); 5.3 Enteric Glial Cells andFunctional Gastrointestinal Disorders; 5.4 Conclusions; References.
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6.4 Differentiating FD andFunctional Esophageal Diseases6.4.1 Difficulty inDifferentiating Between FD andGERD; 6.4.2 Limitations inClinical Symptoms andDiagnosis; 6.5 Future Considerations; References; Chapter 7: Neuro-gastroenterology: Gastroduodenal Function (Motility) andUltrasonographic Assessment; 7.1 Gastrointestinal Motility Disorders; 7.1.1 Test Meal (Consommé Soup); 7.2 Parameters; 7.2.1 Fasting Antral Area (FAA); 7.2.2 Gastric Accommodation Reflex (GAR); 7.2.3 Gastric Emptying (Gastric Emptying Rate: GER); 7.2.4 Antral Contractions (Motility Index: MI).
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Chapter 3: Environmental Factors3.1 Introduction; 3.2 Food andDyspepsia; 3.3 Gastrointestinal Infection andDyspepsia; 3.4 Acute andChronic Stress andDyspepsia; 3.5 Abuse asanEarly-Life Stress; 3.6 Animal Models forFunctional Dyspepsia; 3.7 Duodenal Inflammation asaKey Mechanism; 3.8 Summary andOutlook; References; Part II: Pathophysiology; Chapter 4: Neuro-gastroenterology: Central andAutonomic Nervous System; 4.1 Association ofVarious Stimuli fromGastrointestinal Tracts withCentral Sensation andAbdominal Symptoms inFD; 4.1.1 Gastric Acid (Chemical Stimulation).
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Chapter 6: Neuro-gastroenterology: Esophagogastric Function (Motility)6.1 Basic Esophageal Motor Function; 6.1.1 Upper Esophageal Sphincter (UES); 6.1.2 Primary Peristaltic Contraction; 6.1.3 Secondary Peristaltic Contraction; 6.1.4 Lower Esophageal Sphincter (LES); 6.2 Functional Esophageal Diseases; 6.2.1 Gastroesophageal Reflux Disease (GERD); 6.2.2 Esophageal Motility Disorders; 6.3 The Relationship Between Functional Dyspepsia (FD) andFunctional Esophageal Diseases; 6.3.1 Commonality Between FD andGERD; 6.3.2 Involvement oftheNitroxidergic Nerve withtheEsophagus andStomach.
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| Abstract
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The research and outcomes presented in this book gather evidence concerning both the pathogenesis and treatment of functional dyspepsia. It provides the latest information on this common non-organic disease, indicating its characteristic pathogenesis based on the brain-gut interaction and micro-environment and evidence gleaned from clinical treatment. Since the pathogenesis is associated with psychology, neurology, endocrinology and bacteriology in addition to gastroenterological physiology, it is often intractable and finding a suitable treatment rationale is challenging. Furthermore, the pathogenesis varies around the world and the efficacy of treatment using standard drugs varies among different populations worldwide; accordingly, this book highlights evidence gained in clinical trials in Japan. Functional Dyspepsia is a milestone produced by respected experts. Addressing unique topics and new findings of treatment including challenging and/or future rationales, it offers an invaluable resource for general clinicians, gastroenterologists, and basic researchers alike.
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| Subject
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Indigestion-- Diagnosis.
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Indigestion-- Treatment.
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Endocrinology.
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Gastroenterology.
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HEALTH FITNESS-- Diseases-- General.
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MEDICAL-- Clinical Medicine.
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MEDICAL-- Diseases.
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MEDICAL-- Evidence-Based Medicine.
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MEDICAL-- Internal Medicine.
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Medicine, Psychosomatic.
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Medicine.
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Dyspepsia-- physiopathology.
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Dyspepsia-- therapy.
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| Dewey Classification
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616.332
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| LC Classification
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RC827
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| Added Entry
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Kusunoki, Hiroaki
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Tominaga, Kazunari
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