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BL
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| Record Number
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891258
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| Title & Author
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Biotechnological applications of polyhydroxyalkanoates /\ Vipin Chandra Kalia, editor.
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| Publication Statement
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Singapore :: Springer,, 2019.
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| Page. NO
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1 online resource
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| ISBN
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9789811337598
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: 9789811337604
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: 9811337594
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: 9811337608
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9789811337581
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9811337586
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| Contents
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Intro; Dedication; Preface; Contents; About the Editor; 1: The Dawn of Novel Biotechnological Applications of Polyhydroxyalkanoates; 1.1 Introduction; 1.2 Antimicrobials, Biocontrol and Anticancer Agents; 1.3 Drug Carriers; 1.4 Engineering Tissues; 1.5 Medical Implants and Devices; 1.6 Anti-osteoporosis Agent; 1.7 Memory Enhancer; 1.8 Packaging; 1.9 Agriculture; 1.10 Challenges in Customizing PHAs; 1.11 The Future; References; 2: Strategy for Biosynthesis of Polyhydroxyalkonates Polymers/Copolymers and Their Application in Drug Delivery; 2.1 Introduction
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2.2 Strategy for Biosynthesis of Polyhydroxyalkonates2.2.1 Enhancement of PHA Accumulation and Production; 2.2.2 Approaches to Produce Copolymers; 2.2.2.1 Precursor Feeding; 2.2.2.2 Metabolic Engineering to Synthesize Copolymer Precursors; 2.3 Biodegradability and Biocompatibility of PHA; 2.4 PHA in Drug Delivery; 2.4.1 Intrinsic PHA in Drug Delivery; 2.4.1.1 Nanoparticles; 2.4.1.2 Microsphere; 2.4.1.3 Scaffolds; 2.4.1.4 Nanofibers; 2.4.2 Functionalized PHA in Drug Delivery; 2.4.2.1 Functionalization of PHA Granule Associated Proteins; 2.4.2.2 Functionalized PHA Graft Polymer
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2.4.2.3 Functionalized PHA Block Copolymer2.5 Route for Drug Delivery; 2.5.1 Oral Route; 2.5.2 Intravenous Route; 2.5.3 Subcutaneous Route; 2.6 Drug Release Mechanism; 2.7 Factors Affect Drug Release; 2.8 Conclusion; 2.9 Opinion; References; 3: Applications of Polyhydroxyalkanoates and Their Metabolites as Drug Carriers; 3.1 Introduction; 3.2 Applications of PHA as Drug Carriers; 3.3 Anticancer Carriers; 3.4 Antibacterial Carriers; 3.5 Wound Dressers; 3.6 Conclusion; References; 4: Polyhydroxyalkanoates Applications in Antimicrobial Agents Delivery and Wound Healing
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4.1 Introduction4.2 Bacterial Infections; 4.3 PHAs as Antimicrobial Agents; 4.4 PHAs as Delivery System of Antimicrobial Agents; 4.4.1 PHB; 4.4.2 PHAs, Their Derivatives and Copolymers; 4.5 Antibacterial Activity Against Biofilms; 4.6 PHAs Applications; 4.6.1 PHAs as Delivery Systems for Oral Use; 4.6.2 PHAs in Wound Healing; 4.6.3 PHAs as Bacteriostatic Agents in Animal Production; 4.7 Conclusions: Opinion; References; 5: Polyhydroxyalkanoates Applications in Drug Carriers; 5.1 Introduction; 5.2 Anticancer; 5.3 PHB Microspheres; 5.4 Encapsulation; 5.4.1 Synthesis of Capsules
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5.4.2 Characterization Techniques for PHA Capsules5.4.3 Factors Affecting PHA Capsules Properties; 5.4.4 Properties of PHA Capsules; 5.5 Pharmacokinetics and Biodegradation of PHAs; 5.6 Bio-distribution and Toxicity Studies in Animals; 5.7 Nanoparticles; 5.8 Hydrogels; 5.9 Non-woven Membrane; 5.10 Micelles; 5.11 Bone Repair; 5.12 Anti-proliferative Activity; 5.13 Hemolytic Properties; 5.14 Conclusions; 5.15 Opinion; References; 6: Applications of Polyhydroxyalkanoates Based Nanovehicles as Drug Carriers; 6.1 Introduction; 6.2 Structure of PHA; 6.3 Bacterial PHA
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| Abstract
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This book presents the latest research on the uses of polyhydroxyalkanoates (PHA), introducing readers to these natural, biodegradable polyesters produced by microorganisms, their functions and applications. The individual chapters discuss the various potentials of these bioplastics, which offer an attractive alternative to non-biodegradable plastics. The book also describes the diverse medical and biomedical applications of PHAs, including their use as drug carriers, memory enhancers, and biocontrol agents, and examines their role in creating a more sustainable economy? which is the need of the hour.
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| Subject
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Poly-beta-hydroxyalkanoates.
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| Subject
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Poly-beta-hydroxyalkanoates.
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| Subject
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TECHNOLOGY ENGINEERING-- Chemical Biochemical.
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| Dewey Classification
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668.4/225
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| LC Classification
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TP248.65.P62
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| Added Entry
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Kalia, Vipin Chandra
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