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BL
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| Record Number
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891299
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| Title & Author
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Hirschsprung's disease and the allied disorders : : status quo and future prospects of treatment /\ Tomoaki Taguchi, Hiroshi Matsufuji, Satoshi Ieiri, editors.
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| Publication Statement
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Singapore :: Springer,, [2019]
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| Page. NO
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1 online resource
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| ISBN
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9789811336058
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: 9789811336065
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: 9789811336072
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: 9811336059
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: 9811336067
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: 9811336075
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9789811336058
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| Notes
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10.4 Hirschsprung's Disease Form
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| Bibliographies/Indexes
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Includes bibliographical references.
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| Contents
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Intro; Preface; Contents; 1: Hirschsprung's Disease: A Historical Overview; 1.1 Description of Hirschsprung's Disease; 1.2 Clarification of Pathophysiology; 1.3 Development of the First Successful Surgical Procedure; 1.4 Improvement of the Surgical Procedure; 1.5 Innovation of the Diagnostic Technique; 1.6 Recent Advance of the Research on Genetics and Embryonic Background; 1.7 Further Innovation of the Surgical Procedure; 1.8 Future Tasks; References; 2: Hirschsprung's Disease: Pathogenesis and Overview; 2.1 Historical Aspect; 2.2 Etiology; 2.2.1 Migration of Neural Crest Cells
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2.2.1.1 Cranio-caudal Migration2.2.1.2 Sacral Nerve Compensation; 2.2.2 Microenvironment; 2.2.3 Cell Adhesion Molecules; 2.2.4 Neurotrophic Factors; 2.2.5 Immunologic Response; 2.2.6 Epithelial-Derived Signal; 2.2.7 Autophagy; 2.2.8 Genetics; References; 3: Genetic Aspect of Hirschsprung's Disease; 3.1 Hirschsprung's Disease; 3.2 Epidemiology and Classification; 3.3 Explorations in Genetics of HSCR; 3.4 The RET and the Endothelin Signalling Pathway; 3.5 Interaction Between Pathways; 3.6 Other Genes Related to Non-syndromic HSCR; 3.7 Multigenic Inheritance of Isolated HSCR
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3.8 The Unanswered Question of Male Sex Bias of HSCR3.9 Syndromic HSCR; 3.10 Genetic Counselling; 3.11 Recent Progress and Future Directions; References; 4: Craniocaudal Migration/Neurocristopathy; 4.1 Craniocaudal Migration Theory; 4.2 Neural Crest Cell Migration; 4.3 Neurocristopathy; 4.3.1 Simple and Complex Neurocristopathy; 4.3.2 Complex Neurocristopathies Associated with HD; References; 5: Sacral Pathway Theory of Hirschsprung's Disease; References; 6: Vascular Abnormality and Ischemic Theory; 6.1 Ischemic Theory; 6.2 Abnormal Arteries in Hirschsprung's Disease
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6.3 Abnormal Arteries in Allied Disorders of Hirschsprung's Disease6.4 Experimental Study; 6.5 Discussion; References; 7: Incidence and Sexual Difference; 7.1 Early Investigations on Incidence; 7.2 Incidences Around the World; 7.3 Recent Studies on Incidence; 7.4 Chronological Change of Incidence; 7.5 Difference of Incidence Between Ethnic Groups and Other Factors; 7.6 Sexual Difference; 7.7 Frequency of Types of Hirschsprung's Disease; 7.8 Sexual Difference of Patients with Distinctive Types of Hirschsprung's Disease; 7.9 Familial Incidence of Hirschsprung's Disease
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7.10 Frequency of Hirschsprung's Disease Associated with Down SyndromeReferences; 8: Classification; References; 9: Symptom; 9.1 Introduction; 9.2 Symptoms; 9.2.1 Delayed Passage of Meconium; 9.2.2 Abdominal Symptoms; 9.2.3 Total Colonic Aganglionosis (TCA); 9.2.4 Impact of DS on Symptomatic Presentation; 9.3 Major Diseases Mimicking HD in the Neonatal Period; 9.3.1 Food Allergy; 9.3.2 Congenital Hypothyroidism; 9.4 Closing; References; 10: Hirschsprung's Disease Pathology; 10.1 Introduction; 10.2 Pathological Definition; 10.3 Histological Features
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| Abstract
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This book provides essential information on the status quo and changing profile of Hirschsprung's disease and allied disorders. Hirschsprung's disease is a common cause of neonatal intestinal obstruction and one of the most important and most fascinating diseases in pediatric surgery throughout the world. Currently, the diagnosis and treatment of Hirschsprung's disease and allied disorders are in a state of constant development. Written by expert pediatric surgeons, Hirschsprung's Disease and the Allied Disorders presents state-of-the-art information, such as new genetic evidence, and historical operative techniques that were less invasive and resulted in fewer follow-up operations. It offers a highly informative guide that will greatly benefit all readers engaged in pediatric medicine, pediatric surgeons, and the medical staff of NICUs around the globe.
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| Subject
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Hirschsprung's disease-- Treatment.
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| Subject
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Hirschsprung's disease.
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| Dewey Classification
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616.3/4
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| LC Classification
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RC862.M35H57 2019
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| Added Entry
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Ieiri, Satoshi
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Matsufuji, Hiroshi
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Taguchi, Tomoaki
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