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" Perinatal stem cells : "
Zhong Chao Han, Tsuneo A. Takahashi, Zhibo Han, Zongjin Li, editors.
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BL
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| Record Number
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891566
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| Title & Author
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Perinatal stem cells : : biology, manufacturing and translational medicine /\ Zhong Chao Han, Tsuneo A. Takahashi, Zhibo Han, Zongjin Li, editors.
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| Publication Statement
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Singapore :: Springer,, 2019.
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| Page. NO
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1 online resource (vi, 173 pages) :: illustrations (some color)
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| ISBN
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9789811327032
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: 9789811327049
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: 9811327033
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: 9811327041
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9789811327025
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9811327025
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| Contents
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Intro; Contents; 1: Introduction of Perinatal Tissue-Derived Stem Cells; 1.1 Introduction; 1.2 Perinatal Related Tissues; 1.2.1 Umbilical Cord; 1.2.2 The Structure of the Placenta; 1.2.3 Amniotic Fluid; 1.2.4 Amniotic Membrane; 1.3 Perinatal Stem Cells; 1.3.1 Classification of Perinatal Stem Cells; 1.3.2 Umbilical Cord Blood; 1.3.3 Amniotic Fluid; 1.3.4 Amniotic Membrane; 1.3.5 Placental Stem Cells; 1.3.6 Special Population of Perinatal Stem Cells; 1.4 Prospective of Perinatal Stem Cells; References; 2: The Regenerative and Reparative Potential of Amniotic Membrane Stem Cells
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2.1 Introduction2.2 Key Perinatal Stem Cell Types; 2.2.1 Umbilical Cord/Cord Blood Stem Cells; 2.2.2 Placental/Placental Membrane Stem Cells; 2.2.3 Amniotic Fluid Stem Cells; 2.2.4 Amniotic Membrane-Derived Stem/Stem-Like Cells; 2.3 Future Outlook: Perinatal Stem Cells; 2.3.1 Extracellular Vesicles from Perinatal Stem Cells; 2.4 Conclusion; References; 3: The Stemness of Perinatal Stem Cells; 3.1 Introduction; 3.2 Stemness of ES Cells, iPS Cells, and Adult Stem Cells; 3.2.1 Embryonic Stem Cells; 3.2.2 iPS Cells; 3.2.3 Adult Stem Cells; 3.3 Perinatal Stem Cell
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3.3.1 Hematopoietic Stem Cells3.3.2 Mesenchymal Stem Cells; 3.4 Sources for Perinatal Stem Cell Derivation; 3.4.1 Umbilical Cord; 3.4.2 Umbilical Cord Blood; 3.4.3 Amniotic Fluid; 3.4.4 Amnion; 3.4.5 Placental Tissue; 3.5 Stemness of Perinatal Stem Cells; 3.6 Conclusions and Perspectives; References; 4: Quality Assessment of Umbilical Cord Tissue in Newborn Stem Cell Banking; 4.1 Newborn Stem Cell Banking; 4.2 Umbilical Cord Tissue Banking; 4.3 Quality Assessment of Umbilical Cord Tissue; 4.4 Incorporation of Quality Assessment into Umbilical Cord Tissue Banking
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4.5 Regulatory Considerations4.6 Conclusion; References; 5: Safety and Genetic Stability of Cultured Perinatal Mesenchymal Stem Cells; 5.1 Safety Analysis of Perinatal Mesenchymal Stem Cells in Preclinical Studies; 5.2 Safety Evaluation of Perinatal Mesenchymal Stem Cells in Clinical Trials; 5.3 Potential Safety Concerns and Genetic Stability; 5.4 Future Studies for Safer Clinical Application of Perinatal Mesenchymal Stem Cells; References; 6: Therapeutic Application of Perinatal Mesenchymal Stem Cells in Nervous System Diseases; 6.1 Introduction
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6.2 Preclinical Studies of Perinatal Mesenchymal Stem Cell Therapy for Nervous System Diseases6.2.1 Perinatal Mesenchymal Stem Cells for Stroke; 6.2.1.1 Umbilical Cord Mesenchymal Stem Cells (UC-MSC); 6.2.1.2 Umbilical Cord Blood Mesenchymal Stem Cells (UCB-MSC); 6.2.1.3 Amniotic Membrane or Fluid Mesenchymal Stem Cells (AM/AF-MSC); 6.2.1.4 Placenta Mesenchymal Stem Cells (P-MSC); 6.2.2 Perinatal Mesenchymal Stem Cells for Spinal Cord Injury (SCI); 6.2.3 Perinatal Mesenchymal Stem Cells for Parkinson's Disease (PD); 6.2.4 Perinatal Mesenchymal Stem Cells for Alzheimer's Disease
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| Abstract
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This book provides a comprehensive introduction to various types of perinatal stem cells. Given their unique regenerative abilities, stem cells offer a promising avenue in the treatment of degenerative diseases or injury. Currently, the limitations of postnatal cell sources and expanding efficiency may limit autologous stem cell therapies. Although embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be cultured indefinitely ex vivo, and can differentiate into three germ layers, ethical issues, the teratoma formation of ESCs and oncogenic risk of iPSCs are major obstacles to their clinical application. More recently, perinatal stem cells have been isolated from the umbilical cord, Wharton's Jelly, placenta, amniotic membrane and amniotic fluid, which are normally discarded as medical waste. This book, after describing perinatal stem cells in detail, introduces readers to the various types of perinatal stem cells, addressing their characterization, banking, quality control and stability. Importantly, it also reviews the clinical applications of perinatal stem cells to therapy of diseases. Accordingly, it offers a valuable resource for clinicians, researchers and graduate students alike.
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| Subject
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Stem cells-- Therapeutic use.
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Stem cells.
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Stem cells.
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| Dewey Classification
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616.02/774
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| LC Classification
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QH588.S83
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| Added Entry
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Han, Zhibo
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Han, Zhong Chao
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Li, Zongjin
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Takahashi, Tsuneo A.
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