Editing site analysis in a gymnosperm mitochondrial genome reveals similarities with angiosperm mito...

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" Editing site analysis in a gymnosperm mitochondrial genome reveals similarities with angiosperm mitochondrial genomes "
Salmans, Michael Lee; Chaw, Shu-Miaw; Lin, Ching-Ping; Shih, Arthur Chun-Chieh; Wu, Yu-Wei; Mulligan, R. Michael

Document Type	:	AL
Record Number	:	908477
Doc. No	:	LA9f37r1w2
Title & Author	:	Editing site analysis in a gymnosperm mitochondrial genome reveals similarities with angiosperm mitochondrial genomes [Article]\ Salmans, Michael Lee; Chaw, Shu-Miaw; Lin, Ching-Ping; Shih, Arthur Chun-Chieh; Wu, Yu-Wei; Mulligan, R. Michael
Date	:	2010
Title of Periodical	:	UC Irvine
Abstract	:	Sequence analysis of organelle genomes and comprehensive analysis of C-to-U editing sites from flowering and non-flowering plants have provided extensive sequence information from diverse taxa. This study includes the first comprehensive analysis of RNA editing sites from a gymnosperm mitochondrial genome, and utilizes informatics analyses to determine conserved features in the RNA sequence context around editing sites. We have identified 565 editing sites in 21 full-length and 4 partial cDNAs of the 39 protein-coding genes identified from the mitochondrial genome of Cycas taitungensis. The information profiles and RNA sequence context of C-to-U editing sites in the Cycas genome exhibit similarity in the immediate flanking nucleotides. Relative entropy analyses indicate that similar regions in the 5′ flanking 20 nucleotides have information content compared to angiosperm mitochondrial genomes. These results suggest that evolutionary constraints exist on the nucleotide sequences immediately adjacent to C-to-U editing sites, and similar regions are utilized in editing site recognition.