The origin of antigenic diversity in Plasmodium falciparum.

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" The origin of antigenic diversity in Plasmodium falciparum. "
Rich, SM; Ferreira, MU; Ayala, FJ

Document Type	:	AL
Record Number	:	913167
Doc. No	:	LA8714t9k8
Title & Author	:	The origin of antigenic diversity in Plasmodium falciparum. [Article]\ Rich, SM; Ferreira, MU; Ayala, FJ
Date	:	2000
Title of Periodical	:	UC Irvine
Abstract	:	Most studies of genetic variability of Plasmodium falciparum have focused on protein antigens and the genes that encode them. The consensus is that populations exhibit high levels of genetic polymorphism, most notably the genes encoding surface proteins of the merozoite (Msp1, Msp2) and the sporozoite (Csp). The age and derivation of this variation is a subject that warrants further careful consideration, as discussed here by Stephen Rich, Marcelo Ferreira and Francisco Ayala.