The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders

مرکز و کتابخانه مطالعات اسلامی به زبان های اروپایی

منو

" The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders "
Saric-Bosanac, Suzana; Clark, Ashley K; Sivamani, Raja K; Shi, Vivian Y

Document Type	:	AL
Record Number	:	923127
Doc. No	:	LA8949296f
Language of Document	:	English
Main Entry	:	Saric-Bosanac, Suzana; Clark, Ashley K; Sivamani, Raja K; Shi, Vivian Y
Title & Author	:	The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders [Article]\ Saric-Bosanac, Suzana; Clark, Ashley K; Sivamani, Raja K; Shi, Vivian Y
Title of Periodical	:	Dermatology Online Journal
Volume/ Issue Number	:	26/2
Date	:	2020
Abstract	:	Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity. The pilosebaceous unit is a site for production and metabolism of a number of steroid hormones, including stress and sex hormones. This is an overview of the important role that the cutaneous HPA-like-axis plays in the pathogenesis and treatment of inflammatory pilosebaceous disorders, including acne, rosacea, seborrheic dermatitis, and hidradenitis suppurativa.