Nuclear matrix protein 2 antibody-positive adult dermatomyositis: a case report and review of the li...

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" Nuclear matrix protein 2 antibody-positive adult dermatomyositis: a case report and review of the literature "
Cartron, Alexander M; Osler, Montana; Chung, Catherine; Trinidad, John C

Document Type	:	AL
Record Number	:	923155
Doc. No	:	LA9n50x88m
Language of Document	:	English
Main Entry	:	Cartron, Alexander M; Osler, Montana; Chung, Catherine; Trinidad, John C
Title & Author	:	Nuclear matrix protein 2 antibody-positive adult dermatomyositis: a case report and review of the literature [Article]\ Cartron, Alexander M; Osler, Montana; Chung, Catherine; Trinidad, John C
Title of Periodical	:	Dermatology Online Journal
Volume/ Issue Number	:	26/3
Date	:	2020
Abstract	:	Dermatomyositis is a clinically heterogenous inflammatory myopathy with unique cutaneous features. Myositis-specific antibodies can aid in diagnosis and anticipation of patient prognosis. Herein, we report a 22-year-old man who presented with multifocal erythematous plaques with violaceous papules on his bilateral elbows, neck, and face. He was diagnosed with biopsy-proven dermatomyositis and determined to be seropositive for nuclear matrix protein 2 antibody (NXP-2). He was treated with systemic corticosteroids, then intravenous methylprednisolone and azathioprine, and ultimately achieved greatest treatment response with intravenous immune globulin therapy.