Resolution of pembrolizumab-associated lichenoid dermatitis with a single dose of methotrexate

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" Resolution of pembrolizumab-associated lichenoid dermatitis with a single dose of methotrexate "
Varma, Aakaash; Friedlander, Philip; de Moll, Ellen H; Desman, Garrett; Levitt, Jacob

Document Type	:	AL
Record Number	:	923185
Doc. No	:	LA6348767t
Language of Document	:	English
Main Entry	:	Varma, Aakaash; Friedlander, Philip; de Moll, Ellen H; Desman, Garrett; Levitt, Jacob
Title & Author	:	Resolution of pembrolizumab-associated lichenoid dermatitis with a single dose of methotrexate [Article]\ Varma, Aakaash; Friedlander, Philip; de Moll, Ellen H; Desman, Garrett; Levitt, Jacob
Title of Periodical	:	Dermatology Online Journal
Volume/ Issue Number	:	26/5
Date	:	2020
Abstract	:	We present a 53-year-old woman with severe lichenoid dermatitis secondary to pembrolizumab therapy that was refractory to both topical and oral steroids. After almost three months without improvement, the rash was effectively combated with a single 15mg dose of methotrexate. We hope this case will help guide the management of the cutaneous adverse effects of anti-PD1 immunotherapy.