Dermatomyositis associated with nivolumab therapy for melanoma: a case report and review of the lite...

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" Dermatomyositis associated with nivolumab therapy for melanoma: a case report and review of the literature "
Messer, Alison; Drozd, Brandy; Glitza, Isabella C; Lu, Huifang; Patel, Anisha B

Document Type	:	AL
Record Number	:	923259
Doc. No	:	LA4c21b068
Language of Document	:	English
Main Entry	:	Messer, Alison; Drozd, Brandy; Glitza, Isabella C; Lu, Huifang; Patel, Anisha B
Title & Author	:	Dermatomyositis associated with nivolumab therapy for melanoma: a case report and review of the literature [Article]\ Messer, Alison; Drozd, Brandy; Glitza, Isabella C; Lu, Huifang; Patel, Anisha B
Title of Periodical	:	Dermatology Online Journal
Volume/ Issue Number	:	26/8
Date	:	2020
Abstract	:	We present a rare case of dermatomyositis associated with nivolumab therapy for melanoma. Nivolumab is an immune checkpoint inhibitor that blocks the programmed death-1 (PD1) receptor and has a number of associated immunotherapy related adverse events. Although most are T-cell mediated, some are antibody mediated mimics of classical autoimmune diseases. We review the characteristics of other cases of anti-PD1 associated dermatomyositis and the recent literature to better understand how to classify and treat this challenging immunotherapy related adverse event.