A misdiagnosed melanoma: a case of cutaneous epithelioid malignant peripheral nerve sheath tumor

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" A misdiagnosed melanoma: a case of cutaneous epithelioid malignant peripheral nerve sheath tumor "
Linos, Konstantinos; Warren, Simon

Document Type	:	AL
Record Number	:	923823
Doc. No	:	LA319176xb
Language of Document	:	English
Main Entry	:	Linos, Konstantinos; Warren, Simon
Title & Author	:	A misdiagnosed melanoma: a case of cutaneous epithelioid malignant peripheral nerve sheath tumor [Article]\ Linos, Konstantinos; Warren, Simon
Title of Periodical	:	Dermatology Online Journal
Volume/ Issue Number	:	21/4
Date	:	2015
Abstract	:	Malignant Peripheral Nerve Sheath Tumor (MPNST) is a rare soft tissue sarcoma that can occur in superficial locations. Histologically it is categorized into two variants: a conventional/spindled and an epithelioid variant. The latter one is very rare and can be confused histologically with malignant melanoma as it is diffusely positive for S100-protein. Herein we present a case that was initially misdiagnosed as malignant melanoma and discuss morphological and immunohistochemical clues to reach a correct diagnosis.