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" Atypical propylthiouracil-induced ANCA-positive vasculitis: report of a case with unusual clinical and histopathologic findings "
Mull, Jamie L; Solus, Jason F; Mutizwa, Misha M; Chiang, Herbert C; Rosman, Ilana S; Musiek, Amy
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AL
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| Record Number
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923900
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| Doc. No
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LA3v22b88d
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| Language of Document
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English
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| Main Entry
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Mull, Jamie L; Solus, Jason F; Mutizwa, Misha M; Chiang, Herbert C; Rosman, Ilana S; Musiek, Amy
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| Title & Author
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Atypical propylthiouracil-induced ANCA-positive vasculitis: report of a case with unusual clinical and histopathologic findings [Article]\ Mull, Jamie L; Solus, Jason F; Mutizwa, Misha M; Chiang, Herbert C; Rosman, Ilana S; Musiek, Amy
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| Title of Periodical
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Dermatology Online Journal
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21/8
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| Date
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2015
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| Abstract
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The side effects of propylthiouracil, including cytopenia and vasculitis, are well established. We present an interesting case in which cytopenia and cutaneous vasculopathy occurred concomitantly in a critically ill patient. The patient was initially treated for suspected infection until dermatologic and rheumatologic workup revealed ANCA-positivity and vasculopathy on histopathology, most consistent with an atypical presentation of ANCA-positive vasculitis. Upon initiation of immunosuppressive therapy, the patient’s condition rapidly improved emphasizing the importance of early recognition of this condition.
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