Generalized morphea as the first sign of breast carcinoma: a case report

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" Generalized morphea as the first sign of breast carcinoma: a case report "
Desmond, Bryce L; Blattner, Collin M; Young III, John

Document Type	:	AL
Record Number	:	923953
Doc. No	:	LA2tr4496q
Language of Document	:	English
Main Entry	:	Desmond, Bryce L; Blattner, Collin M; Young III, John
Title & Author	:	Generalized morphea as the first sign of breast carcinoma: a case report [Article]\ Desmond, Bryce L; Blattner, Collin M; Young III, John
Title of Periodical	:	Dermatology Online Journal
Volume/ Issue Number	:	22/2
Date	:	2016
Abstract	:	Generalized morphea is a rare idiopathic form of scleroderma that literally means “hard skin.” Morphea is usually considered an isolated event that is not associated with malignancy. However, case reports of lung, hematologic, and breast cancer occurring simultaneously with large plaque morphea have caused dermatologists to question whether a work-up for malignancy is appropriate. We highlight a case of generalized morphea that preceded invasive ductal carcinoma of the breast and provide a discussion about the possible paraneoplastic origin of generalized morphea and systemic sclerosis (SSc).