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" Prognostic Modeling in Desmoplastic Melanoma Using Different Cutpoints for the Proportion of Desmoplasia "
Ming, Michael E; Nwaneshiudu, Adaobi I; Xu, Xiao-Wei; Karakousis, Giorgos C; Elder, David E; Elenitsas, Rosalie
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AL
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| Record Number
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924132
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LA9mk3k4q5
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| Language of Document
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English
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| Main Entry
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Ming, Michael E; Nwaneshiudu, Adaobi I; Xu, Xiao-Wei; Karakousis, Giorgos C; Elder, David E; Elenitsas, Rosalie
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| Title & Author
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Prognostic Modeling in Desmoplastic Melanoma Using Different Cutpoints for the Proportion of Desmoplasia [Article]\ Ming, Michael E; Nwaneshiudu, Adaobi I; Xu, Xiao-Wei; Karakousis, Giorgos C; Elder, David E; Elenitsas, Rosalie
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Dermatology Online Journal
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22/9
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2016
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| Abstract
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Currently, desmoplastic melanomas are commonly divided into “pure” desmoplastic melanoma (at least 90% desmoplasia histologically) and “mixed” (<90%), with pure having a better prognosis, but our understanding of the relationship between percent desmoplasia and prognosis is incomplete. We sought to determine whether a more refined grading system that examined extent of desmoplasia by percent in 10% increments would be a better prognostic model. We also sought to determine the optimal cutpoint for percent desmoplasia if a single cutpoint were used.
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