Apremilast for treatment of recurrent erythema multiforme

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" Apremilast for treatment of recurrent erythema multiforme "
Chen, Tinley; Levitt, Jacob; Geller, Lauren

Document Type	:	AL
Record Number	:	924157
Doc. No	:	LA15s432gx
Language of Document	:	English
Main Entry	:	Chen, Tinley; Levitt, Jacob; Geller, Lauren
Title & Author	:	Apremilast for treatment of recurrent erythema multiforme [Article]\ Chen, Tinley; Levitt, Jacob; Geller, Lauren
Title of Periodical	:	Dermatology Online Journal
Volume/ Issue Number	:	23/1
Date	:	2017
Abstract	:	Recurrent erythema multiforme with oralinvolvement is therapeutically challenging.Apremilast has been used with success in resolvingthe oral aphthae of Behçet disease, prompting theuse of the drug in patients with oral erosions fromerythema multiforme. Three patients with oralerythema multiforme were given apremilast at dosesof 30-60mg daily. Complete clearance of the lesionswere observed in all three patients, including thoserefractory to other standard therapies. Apremilast maypresent an effective option for recurrent erythemamultiforme for patients who have failed trials antiviraland immunosuppressive therapies.