|
" A case of de novo palmoplantar psoriasis with psoriatic arthritis and autoimmune hypothyroidism after receiving nivolumab therapy "
Elosua-González, Marta; Pampín-Franco, Ana; Mazzucchelli-Esteban, Ramón; Mielgo-Rubio, Xabier; Rodriguez-Vásquez, Ximena; García-Zamora, Elena; López-Estebaranz, Jose Luis
| Document Type
|
:
|
AL
|
| Record Number
|
:
|
924302
|
| Doc. No
|
:
|
LA12n4m6pm
|
| Language of Document
|
:
|
English
|
| Main Entry
|
:
|
Elosua-González, Marta; Pampín-Franco, Ana; Mazzucchelli-Esteban, Ramón; Mielgo-Rubio, Xabier; Rodriguez-Vásquez, Ximena; García-Zamora, Elena; López-Estebaranz, Jose Luis
|
| Title & Author
|
:
|
A case of de novo palmoplantar psoriasis with psoriatic arthritis and autoimmune hypothyroidism after receiving nivolumab therapy [Article]\ Elosua-González, Marta; Pampín-Franco, Ana; Mazzucchelli-Esteban, Ramón; Mielgo-Rubio, Xabier; Rodriguez-Vásquez, Ximena; García-Zamora, Elena; López-Estebaranz, Jose Luis
|
| Title of Periodical
|
:
|
Dermatology Online Journal
|
| Volume/ Issue Number
|
:
|
23/8
|
| Date
|
:
|
2017
|
| Abstract
|
:
|
Nivolumab, a monoclonal antibody against the programmed cell death protein 1 (PD-1), has shown promising results in patients with advanced malignancies, including melanoma, lung cancer, and renal cancer. Immune-related adverse events (irAEs) have been reported, including both organ-specific toxicities and skin toxicities. Herein, we report a case of predominantly palmoplantar psoriasis with severe nail involvement, psoriatic arthritis, and autoimmune hypothyroidism after receiving nivolumab treatment for lung cancer. We also summarize the case reports that have been published previously. The knowledge of these irAEs in patients undergoing anti-PD1 therapy is important since it will enable earlier recognition and appropriate management, with the aim of maintaining effective dose without disruption.
|
| |