Eccrine squamous syringometaplasia in an allogenic stem cell transplant patient undergoing chemother...

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" Eccrine squamous syringometaplasia in an allogenic stem cell transplant patient undergoing chemotherapy "
Nethers, Kevin; Messina, Jane; Seminario-Vidal, Lucia

Document Type	:	AL
Record Number	:	924312
Doc. No	:	LA61w0f2kd
Language of Document	:	English
Main Entry	:	Nethers, Kevin; Messina, Jane; Seminario-Vidal, Lucia
Title & Author	:	Eccrine squamous syringometaplasia in an allogenic stem cell transplant patient undergoing chemotherapy [Article]\ Nethers, Kevin; Messina, Jane; Seminario-Vidal, Lucia
Title of Periodical	:	Dermatology Online Journal
Volume/ Issue Number	:	23/9
Date	:	2017
Abstract	:	Eccrine squamous syringometaplasia (ESS) is a rare finding defined as metaplastic change of the cuboidal epithelial cells of eccrine glands into two or more layers of squamous epithelial cells. We present a patient who developed ESS after induction of CLAG chemotherapy [2-Chlorodeoxyadenosine (2-CdA) with cytarabine (Ara-C) and (granulocyte-colony stimulating factor) G-CSF] for management of the blast crisis of his chronic myelogenous leukemia (CML). Our patient’s ESS eruption presented with a variety of morphologies, thus multiple skin biopsies were taken to determine the possible diagnosis(es). All skin biopsies showed ESS and the eruption resolved with topical corticosteroids after CLAG therapy was finished.