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" Paraneoplastic pemphigus without antibodies to desmoglein 1 and "
Flood, Kelsey; Stroud, Christopher; Lazarov, Zelmira; Vigneswara, Nadarajah; Hsu, Sylvia
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AL
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| Record Number
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924350
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LA46z8v7jv
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| Language of Document
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English
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| Main Entry
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Flood, Kelsey; Stroud, Christopher; Lazarov, Zelmira; Vigneswara, Nadarajah; Hsu, Sylvia
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| Title & Author
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Paraneoplastic pemphigus without antibodies to desmoglein 1 and [Article]\ Flood, Kelsey; Stroud, Christopher; Lazarov, Zelmira; Vigneswara, Nadarajah; Hsu, Sylvia
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| Title of Periodical
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Dermatology Online Journal
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| Volume/ Issue Number
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24/2
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| Date
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2018
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| Abstract
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Paraneoplastic pemphigus is a severe autoimmune blistering disease presenting in the setting of underlying malignancy. Paraneoplastic pemphigus is associated with diffuse painful stomatitis throughout the oral cavity with extension to the lips. The cutaneous findings are varied and have been described as lichenoid, pemphigoid, and targetoid lesions. Herein, we report a patient with paraneoplastic pemphigus whose routine testing led to a diagnosis of pemphigus vulgaris. However, further testing was pursued revealing an antibody profile consistent with paraneoplastic pemphigus. Subsequent neoplastic workup revealed an intra-abdominal mass. Our case represents a subtle, non-classic presentation of paraneoplastic pemphigus and suggests the importance of a comprehensive investigative work-up in atypical cases of pemphigus
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