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" Infantile hemangiomas: our current understanding and treatment options "
Soliman, Yssra S; Khachemoune, Amor
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AL
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| Record Number
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924480
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LA5jt8q9km
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| Language of Document
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English
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| Main Entry
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Soliman, Yssra S; Khachemoune, Amor
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| Title & Author
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Infantile hemangiomas: our current understanding and treatment options [Article]\ Soliman, Yssra S; Khachemoune, Amor
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| Title of Periodical
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Dermatology Online Journal
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24/9
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| Date
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2018
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| Abstract
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Infantile hemangioma (IH) is the most common vascular tumor of infancy, affecting up to 10% of all infants. Our understanding of IH and its management has greatly evolved. The etiology of IH is unclear but hypoxia is thought to play a key role. Furthermore, GLUT1, IGF2, and HIF-1-? are thought to be important mediators. Current management options include active observation, medical treatment, and surgical intervention. The goals of treatment are preventing cosmetic disfiguration, psychosocial distress, and life-threatening complications. Infantile hemangioma should be managed with an individual, patient-centered approach. Generally, uncomplicated IH can be observed up to 18 months. However, IH should be treated in the setting of bleeding, ulceration, functional compromise, or eventual failure to regress.
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