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" Acrodermatitis continua of Hallopeau response to optimized biological therapy "
Adas, Alanoud; Dadban, Ali; Arnault, Jean-Philippe; Chaby, Guillaume; Lok, Catherine
Document Type
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AL
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Record Number
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924546
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Doc. No
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LA93s9w1p3
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Language of Document
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English
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Main Entry
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Adas, Alanoud; Dadban, Ali; Arnault, Jean-Philippe; Chaby, Guillaume; Lok, Catherine
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Title & Author
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Acrodermatitis continua of Hallopeau response to optimized biological therapy [Article]\ Adas, Alanoud; Dadban, Ali; Arnault, Jean-Philippe; Chaby, Guillaume; Lok, Catherine
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Title of Periodical
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Dermatology Online Journal
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Volume/ Issue Number
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25/2
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Date
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2019
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Abstract
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Acrodermatitis continua of Hallopeau, first described in 1890, is an uncommon variant of pustular psoriasis. It presents as a sterile pustular eruption of the tips of fingers and toes. The condition has a chronic, relapsing course and is often resistant to many anti-psoriatic therapies. In the following case, we present our experience of etanercept use in a 61-year-old man. Although initial therapy with high-dose etanercept achieved a rapid, sustained response and remission, the lesions relapsed a few months into a lower, maintenance dosage. This result prompted the use a second biotherapeutic agent ustekinumab, which resulted in complete remission, but required a higher dosage than recommended with reduced dosing intervals.
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