Low-dose naltrexone: a unique treatment for amyopathic dermatomyositis

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" Low-dose naltrexone: a unique treatment for amyopathic dermatomyositis "
Manudhane, Albert P; Schrom, Kory P; Ezaldein, Harib H; Armile, James A

Document Type	:	AL
Record Number	:	924602
Doc. No	:	LA89b75552
Language of Document	:	English
Main Entry	:	Manudhane, Albert P; Schrom, Kory P; Ezaldein, Harib H; Armile, James A
Title & Author	:	Low-dose naltrexone: a unique treatment for amyopathic dermatomyositis [Article]\ Manudhane, Albert P; Schrom, Kory P; Ezaldein, Harib H; Armile, James A
Title of Periodical	:	Dermatology Online Journal
Volume/ Issue Number	:	25/6
Date	:	2019
Abstract	:	Gottron papules, a heliotrope rash, scalp and extremity erythema, pruritus, and fatigue are the characteristic signs and symptoms of amyopathic dermatomyositis (ADM). Amyopathic dermatomyositis is considered a distinct entity from dermatomyositis (DM) because the characteristic muscle weakness and muscle enzyme elevations of DM are absent in ADM. With respects to treatment, ADM treatments have traditionally included topical corticosteroids and/or systemic immunosuppressants and immunomodulators. Herein we present a patient with refractory ADM that was responsive to low-dose naltrexone therapy.