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" A challenging diagnosis of penile sarcomatoid squamous cell carcinoma "
Zhang, Sophia; Khosravi, Hasan; Cardis, Michael; Jedrych, Jaroslaw; Ho, Jonhan; Bunimovich, Yuri
Document Type
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AL
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Record Number
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924631
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Doc. No
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LA0z03z1bj
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Language of Document
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English
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Main Entry
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Zhang, Sophia; Khosravi, Hasan; Cardis, Michael; Jedrych, Jaroslaw; Ho, Jonhan; Bunimovich, Yuri
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Title & Author
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A challenging diagnosis of penile sarcomatoid squamous cell carcinoma [Article]\ Zhang, Sophia; Khosravi, Hasan; Cardis, Michael; Jedrych, Jaroslaw; Ho, Jonhan; Bunimovich, Yuri
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Title of Periodical
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Dermatology Online Journal
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Volume/ Issue Number
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25/10
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Date
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2019
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Abstract
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We report a patient with penile sarcomatoid squamous cell carcinoma (SCC) initially misdiagnosed as condyloma acuminatum. Sarcomatoid SCC is a rare, aggressive, biphasic cancer that often presents a diagnostic challenge and carries a poor prognosis, especially after a delay in diagnosis. Although sarcomatoid SCC may exhibit a broad range of clinical features, the expression of p63 and keratin 34?E12 is a common finding. Our case highlights the importance of accurate clinicopathologic correlation to facilitate a timely diagnosis and management of this rare and highly aggressive malignancy.
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