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" Indeterminate cell histiocytosis that presented clinically as benign cephalic histiocytosis "
Haimovic, Adele; Chernoff, Karen; Hale, Christopher S; Meehan, Shane A; Schaffer, Julie V
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AL
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| Record Number
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924976
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LA23d5k96k
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| Language of Document
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English
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| Main Entry
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Haimovic, Adele; Chernoff, Karen; Hale, Christopher S; Meehan, Shane A; Schaffer, Julie V
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| Title & Author
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Indeterminate cell histiocytosis that presented clinically as benign cephalic histiocytosis [Article]\ Haimovic, Adele; Chernoff, Karen; Hale, Christopher S; Meehan, Shane A; Schaffer, Julie V
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| Title of Periodical
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Dermatology Online Journal
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20/12
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| Date
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2015
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| Abstract
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Indeterminate cell histiocytosis (ICH) is a rare, heterogeneous disorder that is characterized by immunophenotypic features of both Langerhans cell histiocytosis (LCH) and non-LCH. We describe a 12-month-old boy with a four-month history of asymptomatic, small, pink-tan papules on his face. Histopathologic evaluation showed a superficial, dermal infiltrate of histiocytes that was positive for S100, CD1a, CD68, and Factor XIIIa. To our knowledge, this represents the first report of the clinical presentation of benign cephalic histiocytosis with immunohistochemical findings of ICH. We review the classification of histiocytic disorders and the clinical and immunohistochemical features of both ICH and benign cephalic histiocytosis.
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