Primary malignant melanoma of the ovary arising in a cystic teratoma; case report and review of the ...

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" Primary malignant melanoma of the ovary arising in a cystic teratoma; case report and review of the literature "
Lee, James; Magpayo, John; Panchari, Charles; Peng, Shi-Kaung

Document Type	:	AL
Record Number	:	925046
Doc. No	:	LA0tr2b2z9
Language of Document	:	English
Main Entry	:	Lee, James; Magpayo, John; Panchari, Charles; Peng, Shi-Kaung
Title & Author	:	Primary malignant melanoma of the ovary arising in a cystic teratoma; case report and review of the literature [Article]\ Lee, James; Magpayo, John; Panchari, Charles; Peng, Shi-Kaung
Title of Periodical	:	Dermatology Online Journal
Volume/ Issue Number	:	20/10
Date	:	2014
Abstract	:	Primary malignant melanoma of the ovary arising in a cystic teratoma is extremely rare. There is no melanocytic component in the normal ovarian tissue. However, melanocytes may be present in a cystic teratoma of the ovary, especially at the basal layer of squamous epithelium. We report a case of primary malignant melanoma of the ovary arising in a cystic teratoma. We demonstrate junctional activity of melanocytes showing malignant transformation with both radial and vertical growth phases, a feature diagnostic for primary malignant melanoma but not always demonstrated in such cases. We compiled and reviewed twelve cases that are also able to demonstrate junctional activity.