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" Acrokeratoelastoidosis "
Mu, Euphemia W; Mir, Adnan; Meehan, Shane A; Nguyen, Nathalie
Document Type
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AL
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Record Number
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925151
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Doc. No
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LA9hj2k1xq
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Language of Document
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English
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Main Entry
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Mu, Euphemia W; Mir, Adnan; Meehan, Shane A; Nguyen, Nathalie
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Title & Author
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Acrokeratoelastoidosis [Article]\ Mu, Euphemia W; Mir, Adnan; Meehan, Shane A; Nguyen, Nathalie
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Title of Periodical
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Dermatology Online Journal
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Volume/ Issue Number
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21/12
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Date
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2015
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Abstract
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Acrokeratoelastoidosis is a rare palmoplantar keratoderma. We report the case of a 32-year old man with multiple keratotic papules and plaques on the peripheral margins of his hands and feet. Histopathologic evaluation showed compact orthokeratosis; Verhoeff van Gieson stain showed thin and fragmented elastic fibers. The differential diagnosis includes focal acral hyperkeratosis, which has a similar presentation but with normal elastic fibers. Treatment of acrokeratoelastoidosis is often disappointing, with minimal response to topical glucocorticoids, keratolytics, retinoids, cryotherapy, and lasers.
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