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" Polycyclic annular presentation of pemphigus vulgaris with an eosinophil predominance in two pregnant patients "


Document Type : AL
Record Number : 925206
Doc. No : LA89x9z770
Language of Document : English
Main Entry : Küçükoğlu, Rıfkiye; Sun, Gizem Pınar; Kılıç, Sıla
Title & Author : Polycyclic annular presentation of pemphigus vulgaris with an eosinophil predominance in two pregnant patients [Article]\ Küçükoğlu, Rıfkiye; Sun, Gizem Pınar; Kılıç, Sıla
Title of Periodical : Dermatology Online Journal
Volume/ Issue Number : 24/10
Date : 2018
Abstract : Pemphigus during pregnancy has a more complicated course owing to the limitations in treatment options and alterations in the severity and presentation of the clinical features. We would like to present two pemphigus vulgaris (PV) cases associated with pregnancy with an unusual clinical appearance exhibiting polycyclic, annular, vesiculobullous plaques with marked eosinophil infiltration in histopathology. To the best of our knowledge pregnancy-associated pemphigus cases with this particular clinical presentation have not been reported in the literature. Changes in the immunologic and hormonal state during pregnancy may play a role in altering the classic clinical presentation and treatment response of PV.
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