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" Subungual pleomorphic fibroma: a case report and review of the literature "
Halteh, Pierre; Magro, Cynthia M; Lipner, Shari R
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AL
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| Record Number
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925241
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LA9w83z9bq
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| Language of Document
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English
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| Main Entry
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Halteh, Pierre; Magro, Cynthia M; Lipner, Shari R
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| Title & Author
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Subungual pleomorphic fibroma: a case report and review of the literature [Article]\ Halteh, Pierre; Magro, Cynthia M; Lipner, Shari R
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| Title of Periodical
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Dermatology Online Journal
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22/11
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| Date
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2016
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| Abstract
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We describe an interesting case of pleomorphic fibroma of the subungual region in a middle aged woman who presented with a recurrence of thickening, lateral ridging, and a midline split of the right third fingernail, 20 years after initial excision. Histology of the specimen demonstrated hyperchromatic stellate cells within the superficial corneum, which were CD34 positive, consistent with a pleomorphic fibroma. Pleomorphic fibroma is a rare mesenchymal neoplasm characterized by atypical spindled cells amidst a collagenous stroma. It is a benign, slow growing tumor that has only been reported in the subungual region twice previously. Although histology may show cellular atypia, the slow-growing benign nature of the tumor, reassuring features histologically i.e low cellularity, and lack of myxomatous change in the stroma, make a conservative approach to therapy reasonable.
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