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" Localized cutaneous argyria: Report of two patients and literature review "


Document Type : AL
Record Number : 925246
Doc. No : LA4wm1j7pt
Language of Document : English
Main Entry : Beutler, Bryce David; Lee, Robert A; Cohen, Philip R
Title & Author : Localized cutaneous argyria: Report of two patients and literature review [Article]\ Beutler, Bryce David; Lee, Robert A; Cohen, Philip R
Title of Periodical : Dermatology Online Journal
Volume/ Issue Number : 22/11
Date : 2016
Abstract : BackgroundLocalized cutaneous argyria is a rare skin condition caused by direct contact with silver or silver particles. It presents as asymptomatic gray or blue-gray macules that appear similar to blue nevi. Histologic features include brown-colored or black-colored silver granules in the basement membrane and dermis, most commonly surrounding eccrine glands, elastic fibers, and collagen fibrils. The condition is most frequently observed in individuals who are regularly exposed to small silver particles, such as silversmiths and welders. However, localized cutaneous argyria has also been associated with acupuncture needles, silver earrings, and topical medications containing silver nitrate. Although the condition is benign, patients who are concerned about the cosmetic features of localized cutaneous argyria may benefit from laser therapy.
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