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" Cowden syndrome presenting with trichilemmomas "
Ng, Elise; Terushkin, Vitaly; Meehan, Shane A; Ho, Roger; Pomeranz, Miriam Keltz
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AL
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| Record Number
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925267
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LA2743j3qs
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| Language of Document
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English
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| Main Entry
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Ng, Elise; Terushkin, Vitaly; Meehan, Shane A; Ho, Roger; Pomeranz, Miriam Keltz
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| Title & Author
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Cowden syndrome presenting with trichilemmomas [Article]\ Ng, Elise; Terushkin, Vitaly; Meehan, Shane A; Ho, Roger; Pomeranz, Miriam Keltz
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| Title of Periodical
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Dermatology Online Journal
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22/12
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| Date
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2016
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| Abstract
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Cowden syndrome (CS) is a genetic cancerpredisposition syndrome that is associated withgermline mutations in the phosphate and tensinhomologue deleted on chromosome ten (PTEN)tumor suppressor gene. It is characterizedby the formation of benign and malignanttumors. Characteristic benign tumors includetrichilemmommas, acral keratoses, mucocutaneousneuromas, and oral papillomas. The most commonmalignant condition include breast, thyroid, andendometrial cancers. We present a case of a30-year-old woman with CS, who initially presentedwith trichilemmomas that were misdiagnosed ascomedonal acne. Recognition of the presentingfeatures of CS is important to ensure proper referral,management, and treatment for these patients.
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