Clozapine Intoxication Mimicking Acute Stroke

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" Clozapine Intoxication Mimicking Acute Stroke "
Lebin, Jacob A.; Villarreal, Joshua D.; Chen, Betty C.; Hall, M. Kennedy

Document Type	:	AL
Record Number	:	927957
Doc. No	:	LA6sw560pd
Language of Document	:	English
Main Entry	:	Lebin, Jacob A.; Villarreal, Joshua D.; Chen, Betty C.; Hall, M. Kennedy
Title & Author	:	Clozapine Intoxication Mimicking Acute Stroke [Article]\ Lebin, Jacob A.; Villarreal, Joshua D.; Chen, Betty C.; Hall, M. Kennedy
Title of Periodical	:	Clinical Practice and Cases in Emergency Medicine
Volume/ Issue Number	:	2/2
Date	:	2018
Abstract	:	Clozapine is an atypical antipsychotic drug prescribed for treatment-resistant schizophrenia. The risk of adverse hematologic, cardiovascular, and neurologic effects has tempered its use, and reports of overdoses remain rare. We report a case of accidental acute clozapine intoxication in a clozapine-naïve patient, who presented with symptoms mimicking acute stroke and later developed status epilepticus. Clozapine intoxication is a rare presentation in the emergency department with potential for iatrogenic harm if not correctly identified.