Pennies for Your Thoughts: A Case Series of Pancytopenia Due to Zinc-Induced Copper Deficiency in th...

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" Pennies for Your Thoughts: A Case Series of Pancytopenia Due to Zinc-Induced Copper Deficiency in the Same Patient "
Dolcourt, Bram A.; Paxton, James H.; Bora, Keenan M.; Aaron, Cynthia K.

Document Type	:	AL
Record Number	:	928131
Doc. No	:	LA5956p39r
Language of Document	:	English
Main Entry	:	Dolcourt, Bram A.; Paxton, James H.; Bora, Keenan M.; Aaron, Cynthia K.
Title & Author	:	Pennies for Your Thoughts: A Case Series of Pancytopenia Due to Zinc-Induced Copper Deficiency in the Same Patient [Article]\ Dolcourt, Bram A.; Paxton, James H.; Bora, Keenan M.; Aaron, Cynthia K.
Title of Periodical	:	Clinical Practice and Cases in Emergency Medicine
Volume/ Issue Number	:	3/4
Date	:	2019
Abstract	:	A 47-year-old schizophrenic male presented on three separate occasions with pancytopenia and sideroblastic anemia due to copper deficiency from massive zinc penny ingestion. The poisoning was treated differently on each visit: intravenous (IV) copper plus surgical decontamination and chelation with calcium disodium versenate (CaNa2EDTA); IV copper plus whole bowel irrigation; and IV copper with surgical decontamination only. Serum zinc half-lives were 80.0 hours, 233.2 hours, and 83.9 hours, respectively. Importantly, chelation with CaNa2EDTA did not significantly alter the elimination half-life. This is the first reported case of the same patient being treated on three different occasions with three different regimens for this condition.