Bowel Perforation in the Emergency Department Related to Bevacizumab Therapy and Recurrent Ovarian C...

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" Bowel Perforation in the Emergency Department Related to Bevacizumab Therapy and Recurrent Ovarian Cancer "
Ostby, Stuart A.; Olushoga, Michael; Leath III, Charles A.; Burleson, Samuel L.

Document Type	:	AL
Record Number	:	928227
Doc. No	:	LA71c686bc
Language of Document	:	English
Main Entry	:	Ostby, Stuart A.; Olushoga, Michael; Leath III, Charles A.; Burleson, Samuel L.
Title & Author	:	Bowel Perforation in the Emergency Department Related to Bevacizumab Therapy and Recurrent Ovarian Cancer [Article]\ Ostby, Stuart A.; Olushoga, Michael; Leath III, Charles A.; Burleson, Samuel L.
Title of Periodical	:	Clinical Practice and Cases in Emergency Medicine
Volume/ Issue Number	:	4/2
Date	:	2020
Abstract	:	Case Presentation: We describe the presentation to the emergency department of a patient with recurrent ovarian cancer treated with bevacizumab with the complication of bowel perforation. Discussion: We review the frequency and outcomes of bevacizumab-related bowel perforation. We also report the patient’s imaging findings, including the radiologic presentation of free intraperitoneal air and portal venous gas, both indicative of bowel perforation and the need for emergent surgical evaluation. Our case also illustrates the potentially catastrophic side effects of bevacizumab and other targeted oncologic therapies of which emergecny physicians may not be aware.